A guide to the composition and functions of the extracellular matrix
Extracellular matrix (ECM) is a dynamic 3‐dimensional network of macromolecules that
provides structural support for the cells and tissues. Accumulated knowledge clearly …
provides structural support for the cells and tissues. Accumulated knowledge clearly …
The natural cytotoxicity receptors in health and disease
The Natural Cytotoxicity Receptors (NCRs), NKp46, NKp44, and NKp30, were some of the
first human activating Natural Killer (NK) cell receptors involved in the non-MHC-restricted …
first human activating Natural Killer (NK) cell receptors involved in the non-MHC-restricted …
The molecular interaction of collagen with cell receptors for biological function
J Elango, C Hou, B Bao, S Wang… - Polymers, 2022 - mdpi.com
Collagen, an extracellular protein, covers the entire human body and has several important
biological functions in normal physiology. Recently, collagen from non-human sources has …
biological functions in normal physiology. Recently, collagen from non-human sources has …
Advanced application of collagen-based biomaterials in tissue repair and restoration
In tissue engineering, bioactive materials play an important role, providing structural support,
cell regulation and establishing a suitable microenvironment to promote tissue regeneration …
cell regulation and establishing a suitable microenvironment to promote tissue regeneration …
[HTML][HTML] Collagen fibril formation in vitro: From origin to opportunities
DM Darvish - Materials Today Bio, 2022 - Elsevier
Sometimes, to move forward, it is necessary to look back. Collagen type I is one of the most
commonly used biomaterials in tissue engineering and regenerative medicine. There are a …
commonly used biomaterials in tissue engineering and regenerative medicine. There are a …
Fibrillar collagens
J Bella, DJS Hulmes - Fibrous proteins: structures and mechanisms, 2017 - Springer
Fibrillar collagens (types I, II, III, V, XI, XXIV and XXVII) constitute a sub-group within the
collagen family (of which there are 28 types in humans) whose functions are to provide three …
collagen family (of which there are 28 types in humans) whose functions are to provide three …
Osteoclast-associated receptor blockade prevents articular cartilage destruction via chondrocyte apoptosis regulation
DR Park, J Kim, GM Kim, H Lee, M Kim… - Nature …, 2020 - nature.com
Osteoarthritis (OA), primarily characterized by articular cartilage destruction, is the most
common form of age-related degenerative whole-joint disease. No disease-modifying …
common form of age-related degenerative whole-joint disease. No disease-modifying …
Biomaterial functionalization with triple-helical peptides for tissue engineering
JD Malcor, F Mallein-Gerin - Acta Biomaterialia, 2022 - Elsevier
In the growing field of tissue engineering, providing cells in biomaterials with the adequate
biological cues represents an increasingly important challenge. Yet, biomaterials with …
biological cues represents an increasingly important challenge. Yet, biomaterials with …
Collagen type I as a ligand for receptor-mediated signaling
I Boraschi-Diaz, J Wang, JS Mort, SV Komarova - Frontiers in Physics, 2017 - frontiersin.org
Collagens form the fibrous component of the extracellular matrix in all multi-cellular animals.
Collagen type I is the most abundant collagen present in skin, tendons, vasculature, as well …
Collagen type I is the most abundant collagen present in skin, tendons, vasculature, as well …
Role of OSCAR signaling in osteoclastogenesis and bone disease
IR Nedeva, M Vitale, A Elson, JA Hoyland… - Frontiers in cell and …, 2021 - frontiersin.org
Formation of mature bone-resorbing cells through osteoclastogenesis is required for the
continuous remodeling and repair of bone tissue. In aging and disease this process may …
continuous remodeling and repair of bone tissue. In aging and disease this process may …