Macrocycles and medium-sized rings are important in many scientific fields and
technologies but are hard to make using current methods, especially on a large scale …

This review centers on the synthetic strategies employed with indolyl‐ynones. Indolyl‐
ynone, owing to its highly reactive ynone moiety, frequently partakes in dearomatizing …

Indole-ynones have been established as general substrates for radical dearomatizing
spirocyclization cascade reactions. Five distinct and varied synthetic protocols have been …

This Feature Article discusses recent advances in the development of cascade ring
expansion reactions for the synthesis of medium-sized rings and macrocycles. Cascade ring …

An efficient and straightforward synthesis of diversified seleno-azaspiro-2, 5-
cyclohexadienones from N-(4-methoxy aryl) propiolamides using elemental selenium and …

A novel conjugate addition/ring expansion (CARE) cascade reaction sequence is reported
that enables medium-sized ring and macrocyclic bis-lactams to be prepared from primary …

Described herein is a novel copper-catalyzed multifunctionalization of alkyne-tethered
indoles, allowing the practical and efficient synthesis of a diverse array of valuable …

A general electrophilic iodocyclization/nucleophile addition cascade transformation for 1, 2-
alkynediones for the synthesis of various oxygen heterocycles and access to regioselective …

Catalytic fast pyrolysis can effectively solve the pollution and treatment problems of sewage
sludge to realize the green recycling of biomass waste energy. The study on the mechanism …

A novel Brønsted-acid-promoted selective C2–N1 ring-expansion reaction of indoles has
been developed that provides a rapid and efficient protocol for the preparation of fused …