On modeling

DS Novikov, VG Kiselev… - Magnetic resonance in …, 2018 - Wiley Online Library
Map** tissue microstructure with MRI holds great promise as a noninvasive window into
tissue organization at the cellular level. Having originated within the realm of diffusion NMR …

Quantifying brain microstructure with diffusion MRI: Theory and parameter estimation

DS Novikov, E Fieremans, SN Jespersen… - NMR in …, 2019 - Wiley Online Library
We review, systematize and discuss models of diffusion in neuronal tissue, by putting them
into an overarching physical context of coarse‐graining over an increasing diffusion length …

Design and validation of diffusion MRI models of white matter

IO Jelescu, MD Budde - Frontiers in physics, 2017 - frontiersin.org
Diffusion MRI is arguably the method of choice for characterizing white matter microstructure
in vivo. Over the typical duration of diffusion encoding, the displacement of water molecules …

Diffusion kurtosis imaging: an emerging technique for evaluating the microstructural environment of the brain

AJ Steven, J Zhuo, ER Melhem - American journal of …, 2014 - Am Roentgen Ray Soc
OBJECTIVE. Diffusion kurtosis imaging is an emerging technique based on the non-
gaussian diffusion of water in biologic systems. The purpose of this article is to introduce and …

[HTML][HTML] Challenges for biophysical modeling of microstructure

IO Jelescu, M Palombo, F Bagnato… - Journal of Neuroscience …, 2020 - Elsevier
The biophysical modeling efforts in diffusion MRI have grown considerably over the past 25
years. In this review, we dwell on the various challenges along the journey of bringing a …

Brain networks and their relevance for stroke rehabilitation

AG Guggisberg, PJ Koch, FC Hummel… - Clinical …, 2019 - Elsevier
Stroke has long been regarded as focal disease with circumscribed damage leading to
neurological deficits. However, advances in methods for assessing the human brain and in …

Revealing mesoscopic structural universality with diffusion

DS Novikov, JH Jensen, JA Helpern… - Proceedings of the …, 2014 - National Acad Sciences
Measuring molecular diffusion is widely used for characterizing materials and living
organisms noninvasively. This characterization relies on relations between macroscopic …

One diffusion acquisition and different white matter models: how does microstructure change in human early development based on WMTI and NODDI?

IO Jelescu, J Veraart, V Adisetiyo, SS Milla, DS Novikov… - Neuroimage, 2015 - Elsevier
White matter microstructural changes during the first three years of healthy brain
development are characterized using two different models developed for limited clinical …

In vivo quantification of demyelination and recovery using compartment-specific diffusion MRI metrics validated by electron microscopy

IO Jelescu, M Zurek, KV Winters, J Veraart… - Neuroimage, 2016 - Elsevier
There is a need for accurate quantitative non-invasive biomarkers to monitor myelin
pathology in vivo and distinguish myelin changes from other pathological features including …

Diffusion kurtosis imaging probes cortical alterations and white matter pathology following cuprizone induced demyelination and spontaneous remyelination

C Guglielmetti, J Veraart, E Roelant, Z Mai, J Daans… - Neuroimage, 2016 - Elsevier
Although MRI is the gold standard for the diagnosis and monitoring of multiple sclerosis
(MS), current conventional MRI techniques often fail to detect cortical alterations and provide …