[HTML][HTML] Dopamine transporter membrane mobility is bidirectionally regulated by phosphorylation and palmitoylation
M Shetty, DE Bolland, J Morrell, BD Grove… - Current Research in …, 2023 - Elsevier
The primary regulator of dopamine availability in the brain is the dopamine transporter
(DAT), a plasma membrane protein that drives reuptake of released dopamine from the …
(DAT), a plasma membrane protein that drives reuptake of released dopamine from the …
Leaky lessons learned: Efflux prone dopamine transporter variant reveals sex and circuit specific contributions of D2 receptor signalling to neuropsychiatric disease
Aberrant dopamine (DA) signalling has been implicated in various neuropsychiatric
disorders, including attention‐deficit/hyperactivity disorder (ADHD), autism spectrum …
disorders, including attention‐deficit/hyperactivity disorder (ADHD), autism spectrum …
Nanoscopic dopamine transporter distribution and conformation are inversely regulated by excitatory drive and D2 autoreceptor activity
The nanoscopic organization and regulation of individual molecular components in
presynaptic varicosities of neurons releasing modulatory volume neurotransmitters like …
presynaptic varicosities of neurons releasing modulatory volume neurotransmitters like …
Dopamine transporter trafficking and Rit2 GTPase: Mechanism of action and in vivo impact
Following its evoked release, dopamine (DA) signaling is rapidly terminated by presynaptic
reuptake, mediated by the cocaine-sensitive DA transporter (DAT). DAT surface availability …
reuptake, mediated by the cocaine-sensitive DA transporter (DAT). DAT surface availability …
[HTML][HTML] Kappa opioid receptor antagonism rescues genetic perturbation of dopamine homeostasis: Molecular, physiological and behavioral consequences
Aberrant dopamine (DA) signaling is implicated in schizophrenia, bipolar disorder (BPD),
autism spectrum disorder (ASD), substance use disorder, and attention-deficit/hyperactivity …
autism spectrum disorder (ASD), substance use disorder, and attention-deficit/hyperactivity …
Novel fluorescent ligands enable single-molecule localization microscopy of the dopamine transporter
The dopamine transporter (DAT) is critical for spatiotemporal control of dopaminergic
neurotransmission and is the target for therapeutic agents, including ADHD medications …
neurotransmission and is the target for therapeutic agents, including ADHD medications …
The story of the dopamine transporter PET tracer LBT-999: from conception to clinical use
S Chalon, J Vercouillie, P Payoux, JB Deloye… - Frontiers in …, 2019 - frontiersin.org
The membrane dopamine transporter (DAT) is involved in a number of brain disorders and
its exploration by positron emission tomography (PET) imaging is highly relevant for the …
its exploration by positron emission tomography (PET) imaging is highly relevant for the …
Motor transitions' peculiarity of heterozygous DAT rats when offspring of an unconventional KOxWT mating
C Carbone, A Brancato, A Adinolfi, SLML Russo… - Neuroscience, 2020 - Elsevier
Causal factors of psychiatric diseases are unclear, due to gene× environment interactions.
Evaluation of consequences, after a dopamine-transporter (DAT) gene knock-out (DAT-KO) …
Evaluation of consequences, after a dopamine-transporter (DAT) gene knock-out (DAT-KO) …
Ligand-conjugated quantum dots for fast sub-diffraction protein tracking in acute brain slices
LB Thal, VR Mann, D Sprinzen, JR McBride… - Biomaterials …, 2020 - pubs.rsc.org
Semiconductor quantum dots (QDs) have demonstrated utility in long-term single particle
tracking of membrane proteins in live cells in culture. To extend the superior optical …
tracking of membrane proteins in live cells in culture. To extend the superior optical …
Genetic and epigenetic signatures associated with plasma oxytocin levels in children and adolescents with autism spectrum disorder
Abstract Oxytocin (OT), the brain's most abundant neuropeptide, plays an important role in
social salience and motivation. Clinical trials of the efficacy of OT in autism spectrum …
social salience and motivation. Clinical trials of the efficacy of OT in autism spectrum …