Bioconjugation methodologies have proven to play a central enabling role in the recent
development of biotherapeutics and chemical biology approaches. Recent endeavours in …

The discovery of natural RNA enzymes (ribozymes) prompted the pursuit of artificial DNA
enzymes (deoxyribozymes) by in vitro selection methods. A key motivation is the conceptual …

This review discusses supramolecular biofunctional materials, a novel class of biomaterials
formed by small molecules that are held together via noncovalent interactions. The …

Since the initial discovery of ribozymes in the early 1980s, catalytic nucleic acids have been
used in different areas. Compared with protein enzymes, catalytic nucleic acids are …

Protein bioconjugation is an increasingly important field of research, with wide-ranging
applications in areas such as therapeutics and biomaterials. Traditional cysteine and lysine …

As a consequence of the self‐assembly of small organic molecules in water, supramolecular
hydrogels are evolving from serendipitous events during organic synthesis to become a new …

This review summarizes research on the metal-binding properties of catalytic DNAzymes,
towards the goal of understanding the structural properties leading to metal ion specificity …

This review highlights some of the recent advances made in our understanding of the
diversity of tyrosine biochemistry and shows how this has inspired novel applications in …

Deoxyribozymes (DNAzymes) with RNA hydrolysis activity have a tremendous potential as
gene suppression agents for therapeutic applications. The most extensively studied …

Catalytic DNA sequences (deoxyribozymes, DNA enzymes, or DNAzymes) have been
identified by in vitro selection for various catalytic activities. Expanding the limits of DNA …