Drug development is a lengthy and costly process that proceeds through several stages
from target identification to lead discovery and optimization, preclinical validation and …

Tissue engineering is a rapidly-growing approach to replace and repair damaged and
defective tissues in the human body. Every year, a large number of people require bone …

In vitro drug screening is widely used in the development of new drugs, because they
constitute a cost-effective approach to select compounds with more potential for therapy …

Recently, the electrospinning (ES) process has been extensively studied due to its potential
applications in various fields, particularly pharmaceutical and biomedical purposes. The …

Self-assembly of peptides can yield an array of well-defined nanostructures that are highly
attractive nanomaterials for many biomedical applications such as drug delivery. Some of …

This review encompasses the most important advances in liver functions and hepatotoxicity
and analyzes which mechanisms can be studied in vitro. In a complex architecture of nested …

Efficient intracellular drug delivery and target specificity are often hampered by the presence
of biological barriers. Thus, compounds that efficiently cross cell membranes are the key to …

Cancer occurs when cells acquire genomic instability and inflammation, produce abnormal
levels of epigenetic factors/proteins and tumor suppressors, reprogram the energy …

Three-dimensional biomimetic scaffolds have widespread applications in biomedical tissue
engineering because of their nanoscaled architecture, eg, nanofibers and nanopores …

Chronic diabetic wounds represent a huge socioeconomic burden for both affected
individuals and the entire healthcare system. Although the number of available treatment …