In the present article the putative role of environmental factors in schizophrenia is reviewed
and synthesized. Accumulating evidence from recent studies suggests that environmental …

Advanced paternal age (APA) is associated with infertility and other reproductive risks.
Studies looking at APA and outcomes have used different paternal age cut‐offs, which has …

The genetic etiology of autism spectrum disorder (ASD) is multifactorial, but how
combinations of genetic factors determine risk is unclear. In a large family sample, we show …

Genetic material is constantly subjected to genotoxic insults and is critically dependent on
DNA repair. Genome maintenance mechanisms differ in somatic and germ cells as the soma …

Context Maternal and paternal ages are associated with neurodevelopmental disorders.
Objective To examine the relationship between advancing paternal age at birth of offspring …

Though there are multiple routes through which parents can influence their offspring, recent
studies of environmentally induced epigenetic variation have highlighted the role of non …

BACKGROUND Due to various sociological factors, couples in developed countries are
increasingly delaying childbearing. Besides ethical, economical and sociological issues, this …

Background: The objectives of this study were to examine the independent and dependent
associations of maternal and paternal age and risk of offspring autism spectrum disorders …

Introduction: Advanced paternal age (APA) is a reported risk factor for schizophrenia in the
offspring. We performed a meta-analysis of this association, considering the effect of gender …

In this article we review the epidemiologic evidence for adverse health effects in offspring of
fathers of advanced age. First the evidence regarding fetal survival is addressed, and …