A moonlighting job for α-globin in blood vessels

PS Abbineni, S Baid, MJ Weiss - Blood, 2024 - ashpublications.org
Red blood cells express high levels of hemoglobin A tetramer (α2β2) to facilitate oxygen
transport. Hemoglobin subunits and related proteins are also expressed at lower levels in …

Cold-driven hemoglobin evolution in Antarctic notothenioid fishes prior to hemoglobin gene loss in white-blooded icefishes

T Desvignes, I Bista, K Herrera, A Landes… - Molecular Biology …, 2023 - academic.oup.com
Expression of multiple hemoglobin isoforms with differing physiochemical properties likely
helps species adapt to different environmental and physiological conditions. Antarctic …

[HTML][HTML] Emerging concepts in the molecular cell biology and functions of mammalian erythrocytes

SD Kumar, J Ghosh, S Ghosh… - Journal of Biological …, 2025 - Elsevier
Erythrocytes, or red blood cells (RBCs), are essential components of vertebrate blood,
comprising approximately 45% of human blood volume. Their distinctive features, including …

Genomics of secondarily temperate adaptation in the only non-Antarctic icefish

AG Rivera-Colón, N Rayamajhi… - Molecular biology …, 2023 - academic.oup.com
White-blooded Antarctic icefishes, a family within the adaptive radiation of Antarctic
notothenioid fishes, are an example of extreme biological specialization to both the chronic …

Regulation of globin expression in Antarctic fish under thermal and hypoxic stress

D Giordano, P Corti, D Coppola, G Altomonte, J Xue… - Marine Genomics, 2021 - Elsevier
In the freezing waters of the Southern Ocean, Antarctic teleost fish, the Notothenioidei, have
developed unique adaptations to cope with cold, including, at the extreme, the loss of …

[HTML][HTML] Quantitative Proteomics and Network Analysis of Differentially Expressed Proteins in Proteomes of Icefish Muscle Mitochondria Compared with Closely …

G Katyal, B Ebanks, A Dowle, F Shephard, C Papetti… - Biology, 2022 - mdpi.com
Simple Summary Antarctic icefish are unusual in that they are the only vertebrates that
survive without the protein haemoglobin. One way to try and understand the biological …

Effect of hemoglobin on Nile tilapia (Oreochromis niloticus) kidney (NTK) cell line damage

W Wang, C Pan, M Lv, Q Ruan, W Chen… - Fish & Shellfish …, 2022 - Elsevier
Bacteria or viral outbreaks can cause tilapia hemorrhage, ensuring considerable volume of
hemoglobin (Hb) into the tissue. However, the hemoglobin toxicity on tissue and high doses …

[PDF][PDF] Conservation values in the marine environment surrounding Heard Island and McDonald Islands

D Welsford, T Lamb, C Masere, M Sumner - 2024 - antarctica.gov.au
Summary Heard Island and McDonald Islands (HIMI) are an external Territory of Australia,
located approximately 4000 kilometres southwest of Australia in the southern Indian Ocean …

[KNIHA][B] Leveraging a Cancer Drugs Off-Target Effects

M Markovic - 2023 - search.proquest.com
Red blood cells (erythrocytes, RBCs) are common to almost all vertebrate life on earth. In
humans, RBCs circulate for approximately 120 days prior to their phago-cytic destruction by …