Sleep-induced apnea and disordered breathing refers to intermittent, cyclical cessations or
reductions of airflow, with or without obstructions of the upper airway (OSA). In the presence …

Lung ventilation fluctuates widely with behavior but arterial PCO2 remains stable. Under
normal conditions, the chemoreflexes contribute to PaCO2 stability by producing small …

Background—Heart failure is a highly prevalent disorder that continues to be associated
with repeated hospitalizations, high morbidity, and high mortality. Sleep-related breathing …

Obstructive sleep apnea (OSA) is independently associated with death from cardiovascular
diseases, including myocardial infarction and stroke. Myocardial infarction and stroke are …

Conclusion Cardiovascular and cerebrovascular diseases are the most common life-
threatening and debilitating diseases in the industrialized world. However, the incidence …

Several epidemiological studies have identified obstructive sleep apnea (OSA) as a risk
factor for systemic hypertension, but a direct etiologic link between the two disorders has not …

Obstructive sleep apnoea syndrome (OSAS) is a highly prevalent disease and is recognised
as a major public health burden. Large-scale epidemiological studies have demonstrated an …

Rationale: Obstructive sleep apnea, a condition leading to chronic intermittent hypoxia
(CIH), is associated with hyperlipidemia, atherosclerosis, and a high cardiovascular risk. A …

Arterial blood pressure rises at apnea termination, and there is increasing evidence that the
sleep apnea–hypopnea syndrome (SAHS) is associated with daytime hypertension but no …

The consequences of obstructive sleep apnea (OSA) are largely mediated by chronic
intermittent hypoxia and sleep fragmentation. The primary molecular domains affected are …