Metabolic characteristics of hashimoto's thyroiditis patients and the role of microelements and diet in the disease management—An overview

AA Mikulska, M Karaźniewicz-Łada… - International journal of …, 2022 - mdpi.com
Hashimoto's thyroiditis (HT) is the most common autoimmune disease and the leading
cause of hypothyroidism, in which damage to the thyroid gland occurs due to the infiltration …

Association between gut microbiota and autoimmune thyroid disease: a systematic review and meta-analysis

B Gong, C Wang, F Meng, H Wang, B Song… - Frontiers in …, 2021 - frontiersin.org
Background Autoimmune thyroid disease (AITD) is characterized by thyroid dysfunction and
deficits in the autoimmune system. Growing attention has been paid toward the field of gut …

A comprehensive review of thyroid hormone metabolism in the gut and its clinical implications

AC Fenneman, E Bruinstroop, M Nieuwdorp… - Thyroid, 2023 - liebertpub.com
Background: The gut is a target organ of thyroid hormone (TH) that exerts its action via the
nuclear thyroid hormone receptor α1 (TRα1) expressed in intestinal epithelial cells. THs are …

[HTML][HTML] Role of microbiota short-chain fatty acids in the pathogenesis of autoimmune diseases

A Rasouli-Saravani, K Jahankhani, S Moradi… - Biomedicine & …, 2023 - Elsevier
There is emerging evidence that microbiota and its metabolites play an important role in
helath and diseases. In this regard, gut microbiota has been found as a crucial component …

Gut dysbiosis and fecal microbiota transplantation in autoimmune diseases

P Belvoncikova, M Maronek, R Gardlik - International journal of molecular …, 2022 - mdpi.com
Gut microbiota dysbiosis has recently been reported in a number of clinical states, including
neurological, psychiatric, cardiovascular, metabolic and autoimmune disorders. Yet, it is not …

Priming of microglia with dysfunctional gut microbiota impairs hippocampal neurogenesis and fosters stress vulnerability of mice

H He, H He, L Mo, Z You, J Zhang - Brain, Behavior, and Immunity, 2024 - Elsevier
Background Mental disorders may be involved in neuroinflammatory processes that are
triggered by gut microbiota. How gut microbiota influence microglia-mediated sensitivity to …

Optimal thyroid hormone replacement

J Jonklaas - Endocrine reviews, 2022 - academic.oup.com
Hypothyroidism is a common endocrinopathy, and levothyroxine is frequently prescribed.
Despite the basic tenets of initiating and adjusting levothyroxine being agreed on, there are …

Zonulin as a potential therapeutic target in microbiota-gut-brain axis disorders: encouraging results and emerging questions

A Veres-Székely, C Szász, D Pap, B Szebeni… - International journal of …, 2023 - mdpi.com
The relationship between dysbiosis and central nervous diseases has been proved in the
last 10 years. Microbial alterations cause increased intestinal permeability, and the …

High-throughput transcriptomics of 409 bacteria–drug pairs reveals drivers of gut microbiota perturbation

D Ricaurte, Y Huang, RU Sheth, DR Gelsinger… - Nature …, 2024 - nature.com
Many drugs can perturb the gut microbiome, potentially leading to negative health
consequences. However, mechanisms of most microorganism–drug responses have not …

Microbiome metabolites and thyroid dysfunction

P Bargiel, M Szczuko, L Stachowska… - Journal of Clinical …, 2021 - mdpi.com
Thyroid diseases are common conditions that have a negative impact on the health of all
populations. The literature sheds light on the differences in the composition of the intestinal …