Life history theory argues that exposure to early life adversity (ELA) accelerates
development, although existing evidence for this varies. We present a meta-analysis and …

Cardiovascular disease (CVD) is the leading cause of death and disability worldwide, and
experiences of psychological trauma have been associated with subsequent CVD onset …

In seeking to understand mental health and disease, it is fundamental to identify the
biological substrates that draw together the experiences and physiological processes that …

Traumatic stress may chronically affect master homeostatic systems at the crossroads of
peripheral and central susceptibility pathways and lead to the biological embedment of …

Childhood maltreatment (CM) and adverse childhood experiences (ACEs) are two primary
forms of interpersonal victimization that have been associated with a host of deleterious …

Abstract Early-life adversity (ELA), which includes maltreatment, neglect, or severe trauma in
childhood, increases the life-long risk for negative health outcomes. Mitochondria play a key …

Mitochondrial dysfunction has been implicated in major depressive disorder (MDD). A
measure of mitochondrial respiratory chain (RC) enzymatic activity—the Mitochondrial …

Background Several reports suggest that altered mitochondrial DNA copy number (mtDNA-
cn), a common biomarker for aberrant mitochondrial function, is implicated in autism …

Is childhood adversity associated with biological aging, and if so, does sex modify the
association, and do lifestyle and mental health mediate the association? A lifespan analysis …

Although early‐life adversity has been associated with negative consequences during
adulthood, growing evidence shows that such adversity can also lead to subsequent stress …