MG53, a member of the tripartite motif protein family, possesses multiple functionalities due
to its classic membrane repair function, anti-inflammatory ability, and E3 ubiquitin ligase …

Diabetic cardiomyopathy (DCM), one of the most serious complications of diabetes mellitus,
has become recognized as a cardiometabolic disease. In normoxic conditions, the majority …

Ischemic injury to the heart induces mitochondrial dysfunction due to increasing oxidative
stress. MG53, also known as TRIM72, is highly expressed in striated muscle, is secreted as …

Background Cancer cells develop resistance to chemotherapeutic intervention by excessive
formation of stress granules (SGs), which are modulated by an oncogenic protein G3BP2 …

The ubiquitin‐proteasome system, which is one of the systems for cell protein homeostasis
and degradation, happens through the ordered and coordinated action of three types of …

Aging is associated with chronic oxidative stress and inflammation that affect tissue repair
and regeneration capacity. MG53 is a TRIM family protein that facilitates repair of cell …

MG53 is an essential component of the cell membrane repair machinery, participating in the
healing of dermal wounds. Here we develop a novel delivery system using recombinant …

Background: Recently, we discovered a new glucogenic and centrally acting orexigenic
hormone–asprosin. Asprosin is elevated in metabolic syndrome (MS) patients, and its …

Under natural conditions, injured cells can be repaired rapidly through inherent biological
processes. However, in the case of diabetes, cardiovascular disease, muscular dystrophy …

With the increasing incidence of diabetic nephropathy (DN), there is an urgent need to find
effective DN preventive and therapeutic modalities. It is widely believed that effective …