Sample preparation and detection methods in point-of-care devices towards future at-home testing

G Adedokun, M Alipanah, ZH Fan - Lab on a Chip, 2024 - pubs.rsc.org
Timely and accurate diagnosis is critical for effective healthcare, yet nearly half the global
population lacks access to basic diagnostics. Point-of-care (POC) testing offers partial …

Diagnostic assay and technology advancement for detecting SARS-CoV-2 infections causing the COVID-19 pandemic

BC Dhar - Analytical and Bioanalytical Chemistry, 2022 - Springer
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-caused COVID-19
pandemic has transmitted to humans in practically all parts of the world, producing socio …

Molecular testing devices for on-site detection of E. coli in water samples

C Manzanas, E Morrison, YS Kim, M Alipanah… - Scientific Reports, 2023 - nature.com
Escherichia coli (E. coli) cells are present in fecal materials that can be the main source for
disease‐causing agents in water. As a result, E. coli is recommended as a water quality …

Nucleic Acid Amplification‐Based Technologies (NAAT)—Toward Accessible, Autonomous, and Mobile Diagnostics

V Narasimhan, H Kim, SH Lee, H Kang… - Advanced Materials …, 2023 - Wiley Online Library
The ongoing pandemic and increasing frequency of infectious disease outbreaks due to
climate change, urbanization, and global human migration have put great focus on nucleic …

Development and implementation of a simple and rapid extraction-free saliva SARS-CoV-2 RT-LAMP workflow for workplace surveillance

Z Li, JL Bruce, B Cohen, CV Cunningham, WE Jack… - PLoS …, 2022 - journals.plos.org
Effective management of the COVID-19 pandemic requires widespread and frequent testing
of the population for SARS-CoV-2 infection. Saliva has emerged as an attractive alternative …

A valve-enabled sample preparation device with isothermal amplification for multiplexed virus detection at the point-of-care

C Manzanas, MM Alam, JC Loeb, JA Lednicky… - ACS …, 2021 - ACS Publications
Early and accurate detection of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) and influenza viruses at the point-of-care is crucial for reducing disease transmission …

Ultrasensitive detection of intact SARS-CoV-2 particles in complex biofluids using microfluidic affinity capture

DC Rabe, A Choudhury, D Lee, EG Luciani, UK Ho… - Science …, 2025 - science.org
Measuring virus in biofluids is complicated by confounding biomolecules coisolated with
viral nucleic acids. To address this, we developed an affinity-based microfluidic device for …

A novel machine-learning aided platform for rapid detection of urine ESBLs and carbapenemases: URECA-LAMP

LR Castellanos, R Chaffee, H Kumar… - Journal of Clinical …, 2024 - journals.asm.org
Pathogenic gram-negative bacteria frequently carry genes encoding extended-spectrum
beta-lactamases (ESBL) and/or carbapenemases. Of great concern are carbapenem …

[HTML][HTML] Moving towards on-site detection of Shiga toxin-producing Escherichia coli in ready-to-eat leafy greens

A Costa-Ribeiro, A Lamas, A Mora, M Prado… - Current Research in …, 2024 - Elsevier
Rapid identification of Shiga toxin-producing Escherichia coli, or STEC, is of utmost
importance to assure the innocuousness of the foodstuffs. STEC have been implicated in …

[HTML][HTML] A biosensor platform for point-of-care SARS-CoV-2 screening

A Georgas, K Agiannis, V Papakosta, P Priftis… - Biosensors, 2022 - mdpi.com
The COVID-19 pandemic remains a constant threat to human health, the economy, and
social relations. Scientists around the world are constantly looking for new technological …