Biomarkers for diagnosis and therapeutic options in hepatocellular carcinoma
Liver cancer is a global health challenge, causing a significant social-economic burden.
Hepatocellular carcinoma (HCC) is the predominant type of primary liver cancer, which is …
Hepatocellular carcinoma (HCC) is the predominant type of primary liver cancer, which is …
Immunotherapy in liver cancer: overcoming the tolerogenic liver microenvironment
Y Liu, H Yang, T Li, N Zhang - Frontiers in Immunology, 2024 - frontiersin.org
Liver cancer is a major global health concern, ranking among the top causes of cancer-
related deaths worldwide. Despite advances in medical research, the prognosis for liver …
related deaths worldwide. Despite advances in medical research, the prognosis for liver …
Artificial intelligence applied to 'omics data in liver disease: towards a personalised approach for diagnosis, prognosis and treatment
Advancements in omics technologies and artificial intelligence (AI) methodologies are
fuelling our progress towards personalised diagnosis, prognosis and treatment strategies in …
fuelling our progress towards personalised diagnosis, prognosis and treatment strategies in …
Blood biomarkers of hepatocellular carcinoma: a critical review
J Zhao, Z Hu, X Zheng, Y Lin, X Liu, J Zhang… - Frontiers in Cell and …, 2024 - frontiersin.org
Hepatocellular Carcinoma (HCC) is a malignant tumor with high morbidity and mortality
worldwide, which represents a serious threat to human life, health and quality of life. Blood …
worldwide, which represents a serious threat to human life, health and quality of life. Blood …
Multiomics profiling of buffy coat and plasma unveils etiology-specific signatures in hepatocellular carcinoma
Methods We generated whole-transcriptome sequencing (WTS) and targeted proteome data
from buffy coat and plasma samples from HCC patients. By integrating etiological …
from buffy coat and plasma samples from HCC patients. By integrating etiological …
Prospects of liquid biopsy in the prognosis and clinical management of gastrointestinal cancers
Gastrointestinal (GI) cancers account for one-fourth of the global cancer incidence and are
incriminated to cause one-third of cancer-related deaths. GI cancer includes esophageal …
incriminated to cause one-third of cancer-related deaths. GI cancer includes esophageal …
Methylated circulating tumor DNA in hepatocellular carcinoma: A comprehensive analysis of biomarker potential and clinical implications
Q Zhu, J **e, W Mei, C Zeng - Cancer Treatment Reviews, 2024 - Elsevier
The intricate epigenetic landscape of hepatocellular carcinoma (HCC) is profoundly
influenced by alterations in DNA methylation patterns. Understanding these alterations is …
influenced by alterations in DNA methylation patterns. Understanding these alterations is …
VIM-AS1, which is regulated by CpG methylation, cooperates with IGF2BP1 to inhibit tumor aggressiveness via EPHA3 degradation in hepatocellular carcinoma
S Han, JY Ko, S Jung, S Oh, DY Kim, E Kang… - … & Molecular Medicine, 2024 - nature.com
Early tumor recurrence in hepatocellular carcinoma (HCC) remains a challenging area, as
the mechanisms involved are not fully understood. While microvascular invasion is linked to …
the mechanisms involved are not fully understood. While microvascular invasion is linked to …
Multiplex methylation detection assays using a blocking FRET probe with machine learning-assisted quantitative melting curve method targeting early-stage breast …
M Tao, Q Yang, C Huan, Z Zhang, P Li, R Huang… - Chemical Engineering …, 2024 - Elsevier
Breast cancer (BC) is the second most prevalent form of cancer, and poses a significant
threat to public health. DNA methylation is an ideal marker for the early detection of BC …
threat to public health. DNA methylation is an ideal marker for the early detection of BC …
Epigenetic silencing of LDHB promotes hepatocellular carcinoma by remodeling the tumor microenvironment
P Zhang, Y Wan, J Ma, J Gong, Z Zhong, Y Cui… - Cancer Immunology …, 2024 - Springer
Lactate dehydrogenase B (LDHB) reversibly catalyzes the conversion of pyruvate to lactate
or lactate to pyruvate and expressed in various malignancies. However, the role of LDHB in …
or lactate to pyruvate and expressed in various malignancies. However, the role of LDHB in …