Rhabdomyosarcoma

R Dasgupta, J Fuchs, D Rodeberg - Seminars in pediatric surgery, 2016 - Elsevier
A malignant tumor of striated muscle origin, rhabdomyosarcoma (RMS) is a childhood tumor
that has benefited from nearly 30 years of multimodality therapy, culminating in a> 70 …

The nitrogen mustards

MS Highley, B Landuyt, H Prenen, PG Harper… - Pharmacological …, 2022 - Elsevier
The nitrogen mustards are powerful cytotoxic and lymphoablative agents and have been
used for more than 60 years. They are employed in the treatment of cancers, sarcomas, and …

Addition of dose-intensified doxorubicin to standard chemotherapy for rhabdomyosarcoma (EpSSG RMS 2005): a multicentre, open-label, randomised controlled …

G Bisogno, M Jenney, C Bergeron, SG Melcón… - The Lancet …, 2018 - thelancet.com
Background Rhabdomyosarcoma is an aggressive tumour that can develop in almost any
part of the body. Doxorubicin is an effective drug against rhabdomyosarcoma, but its role in …

A review of soft-tissue sarcomas: translation of biological advances into treatment measures

NT Hoang, LA Acevedo, MJ Mann… - Cancer management and …, 2018 - Taylor & Francis
Soft-tissue sarcomas are rare malignant tumors arising from connective tissues and have an
overall incidence of about five per 100,000 per year. While this diverse family of …

The World Health Organization classification of skeletal muscle tumors in pediatric rhabdomyosarcoma: a report from the Children's Oncology Group

ER Rudzinski, JR Anderson… - … of pathology & …, 2015 - meridian.allenpress.com
Context Since 1995, the International Classification of Rhabdomyosarcoma has provided
prognostically relevant classification for rhabdomyosarcoma (RMS) and allowed risk …

Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma

S Pomella, P Sreenivas, BE Gryder, L Wang… - Nature …, 2021 - nature.com
Rhabdomyosarcoma (RMS) is an aggressive pediatric malignancy of the muscle, that
includes Fusion Positive (FP)-RMS harboring PAX3/7-FOXO1 and Fusion Negative (FN) …

Rhabdomyosarcoma in children–current pathologic and molecular classification

I Dziuba, P Kurzawa, M Dopierała, AB Larque… - Polish Journal of …, 2018 - termedia.pl
The last 25 years have brought significant progress in the treatment of sarcomas in children,
especially rhabdomyosarcoma (RMS). Nevertheless, treatment failure in some patients …

Rhabdomyosarcoma: advances in molecular and cellular biology

X Sun, W Guo, JK Shen, HJ Mankin, FJ Hornicek… - Sarcoma, 2015 - Wiley Online Library
Rhabdomyosarcoma (RMS) is the most common soft tissue malignancy in childhood and
adolescence. The two major histological subtypes of RMS are alveolar RMS, driven by the …

Embryonal rhabdomyosarcoma completely resected at diagnosis: The European paediatric Soft tissue sarcoma Study Group RMS2005 experience

C Bergeron, M Jenney, F De Corti, S Gallego… - European Journal of …, 2021 - Elsevier
Background Rhabdomyosarcoma (RMS) is the most common form of soft tissue sarcoma in
children. We report the results of the European paediatric Soft tissue sarcoma Study Group …

Molecular diagnostics in the management of rhabdomyosarcoma

MA Arnold, FG Barr - Expert review of molecular diagnostics, 2017 - Taylor & Francis
Introduction: A classification of rhabdomyosarcoma (RMS) with prognostic relevance has
primarily relied on clinical features and histologic classification as either embryonal or …