Migraine triggers and oxidative stress: a narrative review and synthesis
JM Borkum - Headache: The Journal of Head and Face Pain, 2016 - Wiley Online Library
Background Blau theorized that migraine triggers are exposures that in higher amounts
would damage the brain. The recent discovery that the TRPA1 ion channel transduces …
would damage the brain. The recent discovery that the TRPA1 ion channel transduces …
Diabetes drugs in the fight against Alzheimer's disease
V Boccardi, I Murasecco, P Mecocci - Ageing research reviews, 2019 - Elsevier
Alzheimer's disease (AD) is the most prevalent form of dementia, particularly in old age
subjects. Hyperinsulinemia and insulin resistance, which are known as pathophysiological …
subjects. Hyperinsulinemia and insulin resistance, which are known as pathophysiological …
Hypothalamic glucose sensing: making ends meet
VH Routh, L Hao, AM Santiago, Z Sheng… - Frontiers in systems …, 2014 - frontiersin.org
The neuroendocrine system governs essential survival and homeostatic functions. For
example, growth is needed for development, thermoregulation maintains optimal core …
example, growth is needed for development, thermoregulation maintains optimal core …
SGLT2 inhibitors: A novel therapy for cognitive impairment via multifaceted effects on the nervous system
J Mei, Y Li, L Niu, R Liang, M Tang, Q Cai, J Xu… - Translational …, 2024 - Springer
The rising prevalence of diabetes mellitus has casted a spotlight on one of its significant
sequelae: cognitive impairment. Sodium-glucose cotransporter-2 (SGLT2) inhibitors …
sequelae: cognitive impairment. Sodium-glucose cotransporter-2 (SGLT2) inhibitors …
Mitochondrial pyruvate transport regulates presynaptic metabolism and neurotransmission
Glucose has long been considered the primary fuel source for the brain. However, glucose
levels fluctuate in the brain during sleep or circuit activity, posing major metabolic stress …
levels fluctuate in the brain during sleep or circuit activity, posing major metabolic stress …
Association between severe hypoglycaemia and risk of dementia in patients with type 2 diabetes mellitus: A systematic review and meta‐analysis
MD Gómez‐Guijarro, C Álvarez‐Bueno… - Diabetes/Metabolism …, 2023 - Wiley Online Library
The aim of this systematic review was to analyse whether there is an association between
severe hypoglycaemia and the incidence of dementia in patients with type 2 diabetes …
severe hypoglycaemia and the incidence of dementia in patients with type 2 diabetes …
Intracellular energy controls dynamics of stress-induced ribonucleoprotein granules
T Wang, X Tian, HB Kim, Y Jang, Z Huang… - Nature …, 2022 - nature.com
Energy metabolism and membraneless organelles have been implicated in human diseases
including neurodegeneration. How energy deficiency regulates ribonucleoprotein particles …
including neurodegeneration. How energy deficiency regulates ribonucleoprotein particles …
Pathogenetic pathways of cognitive dysfunction and dementia in metabolic syndrome
YY Borshchev, YP Uspensky, MM Galagudza - Life sciences, 2019 - Elsevier
The prevalence of dementia worldwide is growing at an alarming rate. A number of studies
and meta-analyses have provided evidence for increased risk of dementia in patients with …
and meta-analyses have provided evidence for increased risk of dementia in patients with …
Ameliorative effect of saffron aqueous extract on hyperglycemia, hyperlipidemia, and oxidative stress on diabetic encephalopathy in streptozotocin induced …
Diabetic encephalopathy is one of the severe complications in patients with diabetes
mellitus. Findings indicate that saffron extract has antioxidant properties but its underlying …
mellitus. Findings indicate that saffron extract has antioxidant properties but its underlying …
Zinc: indications in brain disorders
Zinc is the authoritative metal which is present in our body, and reactive zinc metal is crucial
for neuronal signaling and is largely distributed within presynaptic vesicles. Zinc also plays …
for neuronal signaling and is largely distributed within presynaptic vesicles. Zinc also plays …