It is becoming clearer how neurobiological mechanisms generate 'liking'and
'wanting'components of food reward. Mesocorticolimbic mechanisms that enhance …

Behaviours such as eating, copulating, defending oneself or taking addictive drugs begin
with a motivation to initiate the behaviour. Both this motivational drive and the behaviours …

Motivational and motor deficits are common in patients with depression and other psychiatric
disorders, and are related to symptoms of anhedonia and motor retardation. These deficits in …

Drug addiction and obesity appear to share several properties. Both can be defined as
disorders in which the saliency of a specific type of reward (food or drug) becomes …

Because human energy metabolism evolved to favor adiposity over leanness, the
availability of palatable, easily attainable, and calorically dense foods has led to …

Traditional factors that once explained men's sexual difficulties appear insufficient to account
for the sharp rise in erectile dysfunction, delayed ejaculation, decreased sexual satisfaction …

Functional, molecular and genetic neuroimaging has highlighted the existence of brain
anomalies and neural vulnerability factors related to obesity and eating disorders such as …

What we eat, when and how much, all are influenced by brain reward mechanisms that
generate “liking” and “wanting” for foods. As a corollary, dysfunction in reward circuits might …

An increasingly influential perspective conceptualizes both obesity and overeating as a food
addiction accompanied by corresponding brain changes. Because there are far-reaching …

The clinical efficacy of bariatric surgery has encouraged the scientific investigation of the gut
as a major endocrine organ. Manipulation of gastrointestinal anatomy through surgery has …