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[HTML][HTML] Genetic causes and modifiers of autism spectrum disorder
Autism Spectrum Disorder (ASD) is one of the most prevalent neurodevelopmental
disorders, affecting an estimated 1 in 59 children. ASD is highly genetically heterogeneous …
disorders, affecting an estimated 1 in 59 children. ASD is highly genetically heterogeneous …
Genetics of glutamate and its receptors in autism spectrum disorder
Autism spectrum disorder (ASD) is a neurodevelopmental impairment characterized by
deficits in social interaction skills, impaired communication, and repetitive and restricted …
deficits in social interaction skills, impaired communication, and repetitive and restricted …
Genomic architecture of autism from comprehensive whole-genome sequence annotation
Fully understanding autism spectrum disorder (ASD) genetics requires whole-genome
sequencing (WGS). We present the latest release of the Autism Speaks MSSNG resource …
sequencing (WGS). We present the latest release of the Autism Speaks MSSNG resource …
Autism spectrum disorders: etiology and pathology
Autism spectrum disorders (ASD) are a group of neurodevelopmental diseases. The cause
of ASD is unknown, but several genetic and non-genetic risk factors have been …
of ASD is unknown, but several genetic and non-genetic risk factors have been …
Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder
We are performing whole-genome sequencing of families with autism spectrum disorder
(ASD) to build a resource (MSSNG) for subcategorizing the phenotypes and underlying …
(ASD) to build a resource (MSSNG) for subcategorizing the phenotypes and underlying …
The role of gut bacterial metabolites in brain development, aging and disease
In the last decade, emerging evidence has reported correlations between the gut
microbiome and human health and disease, including those affecting the brain. We …
microbiome and human health and disease, including those affecting the brain. We …
Advancing the understanding of autism disease mechanisms through genetics
Progress in understanding the genetic etiology of autism spectrum disorders (ASD) has
fueled remarkable advances in our understanding of its potential neurobiological …
fueled remarkable advances in our understanding of its potential neurobiological …
Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24. 32 and a significant overlap with schizophrenia
Molecular autism, 2017 - Springer
Background Over the past decade genome-wide association studies (GWAS) have been
applied to aid in the understanding of the biology of traits. The success of this approach is …
applied to aid in the understanding of the biology of traits. The success of this approach is …
Autism genetics: opportunities and challenges for clinical translation
Genetic studies have revealed the involvement of hundreds of gene variants in autism. Their
risk effects are highly variable, and they are frequently related to other conditions besides …
risk effects are highly variable, and they are frequently related to other conditions besides …
The autism brain imaging data exchange: towards a large-scale evaluation of the intrinsic brain architecture in autism
Autism spectrum disorders (ASDs) represent a formidable challenge for psychiatry and
neuroscience because of their high prevalence, lifelong nature, complexity and substantial …
neuroscience because of their high prevalence, lifelong nature, complexity and substantial …