Identifying biases and their potential solutions in human microbiome studies
Advances in DNA sequencing technology have vastly improved the ability of researchers to
explore the microbial inhabitants of the human body. Unfortunately, while these studies have …
explore the microbial inhabitants of the human body. Unfortunately, while these studies have …
The human microbiome in evolution
The trillions of microbes living in the gut—the gut microbiota—play an important role in
human biology and disease. While much has been done to explore its diversity, a full …
human biology and disease. While much has been done to explore its diversity, a full …
Colonic bacterial composition in Parkinson's disease
Abstract Introduction We showed that Parkinson's disease (PD) patients have alpha‐
synuclein (α‐Syn) aggregation in their colon with evidence of colonic inflammation. If PD …
synuclein (α‐Syn) aggregation in their colon with evidence of colonic inflammation. If PD …
Small metabolites, possible big changes: a microbiota-centered view of non-alcoholic fatty liver disease
The spectrum of non-alcoholic fatty liver disease (NAFLD) ranges from simple hepatic
steatosis, commonly associated with obesity, to non-alcoholic steatohepatitis, which can …
steatosis, commonly associated with obesity, to non-alcoholic steatohepatitis, which can …
Brain–gut microbiome interactions and functional bowel disorders
EA Mayer, T Savidge, RJ Shulman - Gastroenterology, 2014 - Elsevier
Alterations in the bidirectional interactions between the intestine and the nervous system
have important roles in the pathogenesis of irritable bowel syndrome (IBS). A body of largely …
have important roles in the pathogenesis of irritable bowel syndrome (IBS). A body of largely …
Dietary amino acids and the gut‐microbiome‐immune axis: physiological metabolism and therapeutic prospects
N Ma, X Ma - Comprehensive Reviews in Food Science and …, 2019 - Wiley Online Library
Dietary amino acids (AAs) are not only absorbed and metabolized by enterocytes but also
available to the microbiota in the gut in mammals. In addition to serving as the materials for …
available to the microbiota in the gut in mammals. In addition to serving as the materials for …
Fungal-bacterial interactions in health and disease
Fungi and bacteria encounter each other in various niches of the human body. There, they
interact directly with one another or indirectly via the host response. In both cases …
interact directly with one another or indirectly via the host response. In both cases …
Similar fecal microbiota signatures in patients with diarrhea-predominant irritable bowel syndrome and patients with depression
Y Liu, L Zhang, X Wang, Z Wang, J Zhang… - Clinical …, 2016 - Elsevier
Background & Aims Patients with irritable bowel syndrome (IBS) often have psychiatric
comorbidities. Alterations in the intestinal microbiota have been associated with IBS and …
comorbidities. Alterations in the intestinal microbiota have been associated with IBS and …
Mucosal microbiota of intestinal polyps reveals putative biomarkers of colorectal cancer
The human intestine retains a complex microbial ecosystem, which performs crucial
functions that impact on host health. Several studies have indicated that intestinal dysbiosis …
functions that impact on host health. Several studies have indicated that intestinal dysbiosis …
Inulin-type fructans improve active ulcerative colitis associated with microbiota changes and increased short-chain fatty acids levels
The intestinal microbiota is involved in ulcerative colitis (UC) pathogenesis. Prebiotics are
hypothesized to improve health through alterations to gut microbiota composition and/or …
hypothesized to improve health through alterations to gut microbiota composition and/or …