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Intestinal barrier dysfunction in irritable bowel syndrome: a systematic review
Background and Aim: Irritable bowel syndrome (IBS) is a complex and heterogeneous
disorder. Sensory, motor and barrier dysfunctions are the key physiological endophenotypes …
disorder. Sensory, motor and barrier dysfunctions are the key physiological endophenotypes …
Disorders of the enteric nervous system—a holistic view
The enteric nervous system (ENS) is the largest division of the peripheral nervous system
and closely resembles components and functions of the central nervous system. Although …
and closely resembles components and functions of the central nervous system. Although …
The enteric nervous system in gastrointestinal disease etiology
A highly conserved but convoluted network of neurons and glial cells, the enteric nervous
system (ENS), is positioned along the wall of the gut to coordinate digestive processes and …
system (ENS), is positioned along the wall of the gut to coordinate digestive processes and …
Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas
K Aslan, V Turco, J Blobner, JK Sonner… - Nature …, 2020 - nature.com
Intrinsic malignant brain tumors, such as glioblastomas are frequently resistant to immune
checkpoint blockade (ICB) with few hypermutated glioblastomas showing response …
checkpoint blockade (ICB) with few hypermutated glioblastomas showing response …
New insights into irritable bowel syndrome pathophysiological mechanisms: contribution of epigenetics
G Dothel, MR Barbaro, A Di Vito, G Ravegnini… - Journal of …, 2023 - Springer
Irritable bowel syndrome (IBS) is a complex multifactorial condition including alterations of
the gut–brain axis, intestinal permeability, mucosal neuro-immune interactions, and …
the gut–brain axis, intestinal permeability, mucosal neuro-immune interactions, and …
Genetics of irritable bowel syndrome: shifting gear via biobank-scale studies
The pathophysiology of irritable bowel syndrome (IBS) is multifactorial and probably
involves genetic predisposition and the effect of environmental factors. Unlike other …
involves genetic predisposition and the effect of environmental factors. Unlike other …
[HTML][HTML] Intestinal barrier impairment, preservation, and repair: an update
Background/Objectives: Our objective was to review published studies of the intestinal
barrier and permeability, the deleterious effects of dietary components (particularly fat), the …
barrier and permeability, the deleterious effects of dietary components (particularly fat), the …
The colonic mucosal MicroRNAs, MicroRNA-219a-5p, and MicroRNA-338-3p are downregulated in irritable bowel syndrome and are associated with barrier function …
Background & Aims Alterations in microRNA (miRNA) and in the intestinal barrier are
putative risk factors for irritable bowel syndrome (IBS). We aimed to identify differentially …
putative risk factors for irritable bowel syndrome (IBS). We aimed to identify differentially …
The role of MicroRNA and microbiota in depression and anxiety
Depression and anxiety are devastating disorders. Understanding the mechanisms that
underlie the development of depression and anxiety can provide new hints on novel …
underlie the development of depression and anxiety can provide new hints on novel …
Epigenetic mechanisms in irritable bowel syndrome
Irritable bowel syndrome (IBS) is a brain-gut axis disorder characterized by abdominal pain
and altered bowel habits. IBS is a multifactorial, stress-sensitive disorder with evidence for …
and altered bowel habits. IBS is a multifactorial, stress-sensitive disorder with evidence for …