A leading strategy in tissue engineering is the design of biomimetic scaffolds that stimulate
the body's repair mechanisms through the recruitment of endogenous stem cells to sites of …

More than 85% of the global population requires repair or replacement of a craniofacial
structure. These defects range from simple tooth decay to radical oncologic craniofacial …

To address the growing demand of small-diameter vascular grafts for cardiovascular
disease, it is necessary to develop substitutes with bio-functionalities, such as …

Catch bonds are bonds between a ligand and its receptor that are enhanced by mechanical
force pulling the ligand-receptor complex apart. To date, catch-bond formation has been …

The clinical utility of a small-caliber vascular graft is still limited, owing to the occlusion of
graft by thrombosis and restenosis. A small-caliber vascular graft (diameter, 2.5 mm) …

Most polymeric vascular prosthetic materials have low patency rate for replacement of small
diameter vessels (< 5 mm), mainly due to failure to generate healthy endothelium. In this …

The existing methods of biofabrication for vascular tissue engineering are still bioreactor-
based, extremely expensive, laborious and time consuming and, furthermore, not …

Different tissue types are characterized by varying stiffness and biochemical ligands.
Increasing substrate stiffness has been shown to trigger Yes-associated protein (YAP) …

This study examines the adhesion, spreading, and migration of human umbilical vein
endothelial cells on cross-linked films of artificial extracellular matrix (aECM) proteins. The …

As tissue engineering and regenerative medicine are staged to enter the medical care
setting, the integration of these newly formed tissues with themselves and the surrounding …