Voltage-gated ion channels (VGICs), including those for Na+, Ca2+ and K+, selectively
permeate ions across the cell membrane in response to changes in membrane potential …

Background: The Dietary Approaches to Stop Hypertension (DASH) dietary pattern, which
emphasizes fruit, vegetables, fat-free/low-fat dairy, whole grains, nuts and legumes, and …

Hypokalemia is a common electrolyte disturbance, especially in hospitalized patients. It can
have various causes, including endocrine ones. Sometimes, hypokalemia requires urgent …

Human-based modelling and simulations are becoming ubiquitous in biomedical science
due to their ability to augment experimental and clinical investigations. Cardiac …

Metal ions widely exist in biological systems and participate in many vital biochemical
processes. Monitoring and analyzing metal ions in biological systems can help reveal …

Potassium is an essential nutrient that performs a vital role in cellular functions including
maintaining fluid balance and osmolality of cells. Potassium balance is maintained by the …

G-quadruplexes (G4s) are non-canonical nucleic acid secondary structures that have
gathered significant interest in medicinal chemistry over the past two decades due to their …

The tumor microenvironment (TME) demonstrates distinct hallmarks, including acidosis,
hypoxia, reactive oxygen species (ROS) generation, and altered ion fluxes, which are crucial …

Potassium ion (K+) is the most abundant metal ion in cells and plays an indispensable role
in practically all biological systems. Although there have been reports of both synthetic and …

Electrolyte disorders are very common complications in cancer patients. They might be
associated to a worsening outcome, influencing quality of life, possibility to receive …