Directed evolution has emerged as a powerful strategy to engineer various properties of
proteins. Traditional methods to construct libraries such as error-prone PCR and DNA …

Protein structures are valuable tools to understand protein function. Nonetheless, proteins
are often considered as rigid macromolecules while their structures exhibit specific flexibility …

Heat shock proteins (HSPs) are a type of functionally related proteins present in all living
organisms, both prokaryotes and eukaryotes. They play essential roles in protein–protein …

World widely, Fungal infections have become a serious issue for human beings. Fungal
infections normally happen once invading fungus appear on a specific area of the body and …

Cancer is a fatal disease, responsible for one-quarter of all deaths in developed countries.
Traditional anticancer therapies such as, chemotherapy and radiation, are highly expensive …

RNA-protein complexes are essential in mediating important fundamental cellular
processes, such as transport and localization. In particular, ncRNA-protein interactions play …

Bioluminescent proteins (BLPs) are a class of proteins that widely distributed in many living
organisms with various mechanisms of light emission including bioluminescence and …

Background As molecular biology is creating an increasing amount of sequence and
structure data, the multitude of software to analyze this data is also rising. Most of the …

The functional properties of a protein primarily depend on its three-dimensional (3D)
structure. These properties have classically been assigned, visualized and analysed on the …

Protein structures are valuable tools for understanding protein function. However, protein
dynamics is also considered a key element in protein function. Therefore, in addition to …