Retinal photoreceptor cells contain a specialized outer segment (OS) compartment that
functions in the capture of light and its conversion into electrical signals in a process known …

The transmembrane proteins of the tetraspanin superfamily are implicated in a diverse
range of biological phenomena, including cell motility, metastasis, cell proliferation and …

PURPOSE: To characterize ocular abnormalities associated with iris atrophy in DBA/2J mice
and to determine whether mice of this strain develop elevated intraocular pressure (IOP) and …

Unequalled in scope, depth, and clinical precision, Retina, 5th Edition keeps you at the
forefront of today's new technologies, surgical approaches, and diagnostic and therapeutic …

Retinitis pigmentosa (RP) is a group of inherited human diseases in which photoreceptor
degeneration leads to visual loss and eventually to blindness. Although mutations in the …

Methodological and conceptual advances in human genetics have led to the identification of
an impressive number of human disease genes. This wealth of information has also …

Mutations in the retinal degeneration, retinal degeneration slotilperipherin) and rhodopsin
genes cause photoreceptor degeneration in humans and mice. Although the phenotypes …

Centrosome-and cilia-associated proteins play crucial roles in establishing polarity and
regulating intracellular transport in post-mitotic cells. Using genetic map** and positional …

Retinitis pigmentosa (RP) and allied diseases are heterogeneous clinically and genetically.
Here we summarize the retinal cell types involved in these diseases, the large number of …

Familial macular degeneration is a clinically and genetically heterogeneous group of
disorders characterized by progressive central vision loss. Here we show that an R373C …