Glycoconjugates: synthesis, functional studies, and therapeutic developments

SS Shivatare, VS Shivatare, CH Wong - Chemical reviews, 2022 - ACS Publications
Glycoconjugates are major constituents of mammalian cells that are formed via covalent
conjugation of carbohydrates to other biomolecules like proteins and lipids and often …

Global view of human protein glycosylation pathways and functions

KT Schjoldager, Y Narimatsu, HJ Joshi… - … reviews Molecular cell …, 2020 - nature.com
Glycosylation is the most abundant and diverse form of post-translational modification of
proteins that is common to all eukaryotic cells. Enzymatic glycosylation of proteins involves a …

Helicobacter pylori and Its Role in Gastric Cancer

VE Reyes - Microorganisms, 2023 - mdpi.com
Gastric cancer is a challenging public health concern worldwide and remains a leading
cause of cancer-related mortality. The primary risk factor implicated in gastric cancer …

Gut biogeography of the bacterial microbiota

GP Donaldson, SM Lee, SK Mazmanian - Nature Reviews Microbiology, 2016 - nature.com
Animals assemble and maintain a diverse but host-specific gut microbial community. In
addition to characteristic microbial compositions along the longitudinal axis of the intestines …

Glycosylation in cancer: mechanisms and clinical implications

SS Pinho, CA Reis - Nature Reviews Cancer, 2015 - nature.com
Despite recent progress in understanding the cancer genome, there is still a relative delay in
understanding the full aspects of the glycome and glycoproteome of cancer. Glycobiology …

Helicobacter pylori: an up-to-date overview on the virulence and pathogenesis mechanisms

HC Sharndama, IE Mba - Brazilian Journal of Microbiology, 2022 - Springer
Helicobacter pylori is an organism associated with ulcer disease and gastric cancer. The
latter is one of the most prevalent malignancies and currently the fourth major cause of …

[HTML][HTML] Helicobacter pylori infection: An overview of bacterial virulence factors and pathogenesis

CY Kao, BS Sheu, JJ Wu - Biomedical journal, 2016 - Elsevier
Helicobacter pylori pathogenesis and disease outcomes are mediated by a complex
interplay between bacterial virulence factors, host, and environmental factors. After H. pylori …

Blood groups in infection and host susceptibility

L Cooling - Clinical microbiology reviews, 2015 - journals.asm.org
Blood group antigens represent polymorphic traits inherited among individuals and
populations. At present, there are 34 recognized human blood groups and hundreds of …

Mucins and their role in sha** the functions of mucus barriers

CE Wagner, KM Wheeler… - Annual review of cell and …, 2018 - annualreviews.org
We review what is currently understood about how the structure of the primary solid
component of mucus, the glycoprotein mucin, gives rise to the mechanical and biochemical …

The role of O-glycosylation in human disease

A Magalhães, HO Duarte, CA Reis - Molecular Aspects of Medicine, 2021 - Elsevier
O-glycosylation is a highly frequent post-translation modification of proteins, with important
functional implications in both physiological and disease contexts. The biosynthesis of O …