With the gradual demographic shift toward an aging and obese society, an increasing
number of patients are suffering from bone and cartilage injuries. However, conventional …

Osteoarthritis is the most prevalent chronic and debilitating joint disease, resulting in huge
medical and socioeconomic burdens. Intra-articular administration of agents is clinically …

Real-time sensing of nitric oxide (NO) in physiological environments is critically important in
monitoring neurotransmission, inflammatory responses, cardiovascular systems, etc …

Nanomedicines with controlled drug release have received increasing attention as an
advanced therapeutic strategy for bone diseases. To traverse biological barriers towards …

Nanosensors are now being used to detect and monitor physical characteristics such as the
temperature at nanoscale, with chemical species and nanoparticles. It is nanoscale devices …

Nanomaterials have the potential to improve how patients are clinically treated and
diagnosed. While there are a number of nanomaterials that can be used toward improved …

As nitric oxide (NO) plays significant roles in a variety of physiological processes, the
capability for real-time and accurate detection of NO in live organisms is in great demand …

Cartilage is a key component in joints because of its load-bearing and lubricating abilities.
However, osteoarthritis often leads to afunction of load-bearing/lubrication and occurrence …

Osteoarthritis (OA) microenvironment is marked by matrix metalloproteinases-13 (MMP-13)
overexpression and weak acidity, making it possible to develop dual-stimuli responsive …

Osteoarthritis (OA) is a chronic joint disease and its progression and pathogenesis are
highly associated with the significant increase of joint friction and overproduction of reactive …