The potential role of iNOS in ovarian cancer progression and chemoresistance

M Kielbik, I Szulc-Kielbik, M Klink - International Journal of Molecular …, 2019 - mdpi.com
Inducible nitric oxide synthase (iNOS), the enzyme responsible for nitric oxide (NO)
production, is not present in most cells under normal conditions. The expression of its …

Mass spectrometry-assisted gel-based proteomics in cancer biomarker discovery: approaches and application

R Huang, Z Chen, L He, N He, Z **, Z Li, Y Deng… - …, 2017 - pmc.ncbi.nlm.nih.gov
There is a critical need for the discovery of novel biomarkers for early detection and targeted
therapy of cancer, a major cause of deaths worldwide. In this respect, proteomic …

[HTML][HTML] Patient inflammatory status and CD4+/CD8+ intraepithelial tumor lymphocyte infiltration are predictors of outcomes in high-grade serous ovarian cancer

MP Pinto, C Balmaceda, ML Bravo, S Kato… - Gynecologic …, 2018 - Elsevier
Background High-grade serous ovarian cancer (HGSOC) is the most prevalent and
aggressive histologic type of ovarian cancer. To date, there are no reliable biomarkers to …

Diagnostic and prognostic significance of Ki-67 immunohistochemical expression in surface epithelial ovarian carcinoma

ASA MAhAdevAPPA, SM Krishna… - Journal of clinical and …, 2017 - pmc.ncbi.nlm.nih.gov
Introduction The Surface Epithelial Ovarian Carcinoma (SEOC) at the moment of diagnosis,
the disease is extended beyond the structures of the pelvis. Ki-67 is one of the prognostic …

Patterns of treatment and outcomes in epithelial ovarian cancer: a retrospective north indian single-institution experience

RK Meena, NA Syed, ZA Sheikh, FR Guru… - JCO Global …, 2022 - ascopubs.org
PURPOSE Ovarian cancer (OC) is ranked as the third most common gynecologic cancer in
various Indian cancer registries. In India, OC is seen in the younger age group, with a …

Exploring a multiparameter MRI–based radiomics approach to predict tumor proliferation status of serous ovarian carcinoma

L Liu, L Zhao, Y **g, D Li, H Linghu, H Wang… - Insights into …, 2024 - Springer
Objectives To develop a multiparameter magnetic resonance imaging (MRI)-based
radiomics approach that can accurately predict the tumor cell proliferation status of serous …

New approaches in ovarian cancer based on genetics and carcinogenesis hypotheses

RAM Mogos, R Popovici… - Experimental and …, 2022 - spandidos-publications.com
Ovarian cancer is the leading cause of death among gynecological malignancies and its
incidence is rising in the last decades especially in developed countries. High-grade serous …

[HTML][HTML] Meta-analysis identifying epithelial-derived transcriptomes predicts poor clinical outcome and immune infiltrations in ovarian cancer

D Li, A Tulahong, MN Uddin, H Zhao… - Mathematical …, 2021 - aimspress.com
Previous studies revealed that the epithelial component is associated with the modulation of
the ovarian tumor microenvironment (TME). However, the identification of key transcriptional …

Molecular genetics complexity impeding research progress in breast and ovarian cancers

I Gupta, I Burney… - … and clinical oncology, 2017 - spandidos-publications.com
Breast and ovarian cancer are heterogeneous diseases. While breast cancer accounts for
25% of cancers worldwide, ovarian cancer accounts for 3.5% of all cancers and it is …

Expression of circulating microRNA-141 in epithelial ovarian cancer

AS Fitriawan, AI Kartika, SN Chasanah… - … Journal of Medical …, 2020 - pmc.ncbi.nlm.nih.gov
Background Epithelial ovarian cancer (EOC) is a lethal disease due to late diagnosis and
lack of effective screening methods. MicroRNA (miR/miRNA) plays an important role in …