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Genetics of fat tissue accumulation in pigs: a comparative approach
Fatness traits are important in pig production since they influence meat quality and fattening
efficiency. On the other hand, excessive fat accumulation in humans has become a serious …
efficiency. On the other hand, excessive fat accumulation in humans has become a serious …
Diversity across major and candidate genes in European local pig breeds
The aim of this work was to analyse the distribution of causal and candidate mutations
associated to relevant productive traits in twenty local European pig breeds. Also, the …
associated to relevant productive traits in twenty local European pig breeds. Also, the …
Expression-based GWAS identifies variants, gene interactions and key regulators affecting intramuscular fatty acid content and composition in porcine meat
The aim of this work is to better understand the genetic mechanisms determining two
complex traits affecting porcine meat quality: intramuscular fat (IMF) content and its fatty acid …
complex traits affecting porcine meat quality: intramuscular fat (IMF) content and its fatty acid …
Disruption of the ZBED6 binding site in intron 3 of IGF2 by CRISPR/Cas9 leads to enhanced muscle development in Liang Guang Small Spotted pigs
X Liu, H Liu, M Wang, R Li, J Zeng, D Mo, P Cong… - Transgenic …, 2019 - Springer
Insulin-like growth factor 2 (IGF2) plays an important role in the development of the foetus
and in post-natal growth and development. A SNP within intron 3 of porcine IGF2 disrupts a …
and in post-natal growth and development. A SNP within intron 3 of porcine IGF2 disrupts a …
QTL for microstructural and biophysical muscle properties and body composition in pigs
K Wimmers, I Fiedler, T Hardge, E Murani… - BMC genetics, 2006 - Springer
Background The proportion of muscle fibre types and their size affect muscularity as well as
functional properties of the musculature and meat quality. We aimed to identify QTL for …
functional properties of the musculature and meat quality. We aimed to identify QTL for …
The insulin-like growth factor 2 (IGF2) gene intron3-g.3072G>A polymorphism is not the only Sus scrofa chromosome 2p mutation affecting meat production and carcass traits in …
The objective of this study was to evaluate the effects of mutations in 2 genes [IGF2 and
cathepsin D (CTSD)] that map on the telomeric end of the p arm of SSC2. In this region, an …
cathepsin D (CTSD)] that map on the telomeric end of the p arm of SSC2. In this region, an …
Combined line-cross and half-sib QTL analysis in Duroc–Pietrain population
G Liu, JJ Kim, E Jonas, K Wimmers, S Ponsuksili… - Mammalian …, 2008 - Springer
A Duroc–Pietrain resource population was built to detect quantitative trait loci (QTL) that
affect growth, carcass composition, and pork quality. The data were analyzed by applying …
affect growth, carcass composition, and pork quality. The data were analyzed by applying …
A domesticated transposon mediates the effects of a single‐nucleotide polymorphism responsible for enhanced muscle growth
Single‐nucleotide polymorphisms (SNPs) in the regulatory regions of the genome can have
a profound impact on phenotype. The G3072A polymorphism in intron 3 of insulin‐like …
a profound impact on phenotype. The G3072A polymorphism in intron 3 of insulin‐like …
Analysis of porcine IGF2 gene expression in adipose tissue and its effect on fatty acid composition
L Criado-Mesas, M Ballester, D Crespo-Piazuelo… - PLoS …, 2019 - journals.plos.org
IGF2: g. 3072G> A polymorphism has been described as the causal mutation of a maternally
imprinted QTL for muscle growth and fat deposition in pigs. The objective of the current work …
imprinted QTL for muscle growth and fat deposition in pigs. The objective of the current work …
The effects of two alleles of IGF2 on fat content in pig carcasses and pork
C Burgos, A Galve, C Moreno, J Altarriba, R Reina… - Meat science, 2012 - Elsevier
The different fat infiltration capabilities of two alleles of IGF2 (G3072A) have been
investigated in pigs of a Landrace–Large White× Duroc cross. Paternally inherited G allele …
investigated in pigs of a Landrace–Large White× Duroc cross. Paternally inherited G allele …