Organoids are 3D structures grown from pluripotent stem cells derived from human tissue
and serve as in vitro miniature models of human organs. Organoids are expected to …

Rapid progress in biotechnology has introduced a host of pressing ethical and policy issues
pertaining to stem cell research. In this review, we provide an overview of the most …

The discovery of induced pluripotent stem cells (iPSCs) and the concurrent development of
protocols for their cell-type-specific differentiation have revolutionized our approach to cell …

Human induced pluripotent stem cells (iPSCs) can be limitlessly expanded and
differentiated into almost all cell types. Moreover, they are amenable to gene manipulation …

Integration of physiologically relevant in vitro assays at the earliest stages of drug discovery
may improve the likelihood of successfully translating preclinical discoveries to the clinic …

At present, no effective cure or prophylaxis exists for Alzheimer's disease. Symptomatic
treatments are modestly effective and offer only temporary benefit. Advances in induced …

Current advances in biotechnology open up unprecedented possibilities to transform human
tissues into complex, valuable tissue products, such as organoids. Here, we propose …

Biomedical advances in vision research have been greatly facilitated by the clinical
accessibility of the visual system, its ease of experimental manipulation, and its ability to be …

The central nervous system (CNS) has a highly complex biophysical and biochemical
environment. Despite decades of intensive research, it is still an enormous challenge to …

Alzheimer's disease (AD), a progressive neurodegenerative disorder featuring memory loss
and cognitive impairment, is caused by synaptic failure and the excessive accumulation of …