Resting-state brain connectivity in healthy young and middle-aged adults at risk of progressive Alzheimer's disease

L Kucikova, J Goerdten, ME Dounavi, E Mak… - Neuroscience & …, 2021 - Elsevier
Functional brain connectivity of the resting-state networks has gained recent attention as a
possible biomarker of Alzheimer's Disease (AD). In this paper, we review the literature of …

The Effects of APOEe4 Allele on Cerebral Structure, Function, and Related Interactions with Cognition in Young Adults

L Kucikova, X **ong, P Reinecke, J Madden… - Ageing Research …, 2024 - Elsevier
In the last decade, extensive research has emerged into understanding the impact of risk
factors for Alzheimer's Disease (AD) on brain in pre-symptomatic stages. We investigated …

Investigating brain aging trajectory deviations in different brain regions of individuals with schizophrenia using multimodal magnetic resonance imaging and brain-age …

JD Zhu, YF Wu, SJ Tsai, CP Lin, AC Yang - Translational Psychiatry, 2023 - nature.com
Although many studies on brain-age prediction in patients with schizophrenia have been
reported recently, none has predicted brain age based on different neuroimaging modalities …

Network complexity as a measure of information processing across resting-state networks: evidence from the Human Connectome Project

IM McDonough, K Nashiro - Frontiers in human neuroscience, 2014 - frontiersin.org
An emerging field of research focused on fluctuations in brain signals has provided
evidence that the complexity of those signals, as measured by entropy, conveys important …

Increased brain entropy of resting-state fMRI mediates the relationship between depression severity and mental health-related quality of life in late-life depressed …

C Lin, SH Lee, CM Huang, GY Chen, PS Ho… - Journal of affective …, 2019 - Elsevier
Background Entropy analysis is a computational method used to quantify the complexity in a
system, and loss of brain complexity is hypothesized to be related to mental disorders. Here …

Decreased resting‐state brain activity complexity in schizophrenia characterized by both increased regularity and randomness

AC Yang, CJ Hong, YJ Liou, KL Huang… - Human brain …, 2015 - Wiley Online Library
Schizophrenia is characterized by heterogeneous pathophysiology. Using multiscale
entropy (MSE) analysis, which enables capturing complex dynamics of time series, we …

Applications of resting-state functional connectivity to neurodegenerative disease

J Zhou, S Liu, KK Ng, J Wang - Neuroimaging Clinics, 2017 - neuroimaging.theclinics.com
Neurodegeneration, characterized by gradual and selective spreading of pathologic
changes in a target brain network, leads to specific behavioral and cognitive dysfunctions …

The association of aging with white matter integrity and functional connectivity hubs

AC Yang, SJ Tsai, ME Liu, CC Huang… - Frontiers in aging …, 2016 - frontiersin.org
Normal aging is associated with reduced cerebral structural integrity and altered functional
brain activity, yet the association of aging with the relationship between structural and …

Genetic influence on ageing-related changes in resting-state brain functional networks in healthy adults: A systematic review

H Foo, KA Mather, J Jiang, A Thalamuthu… - Neuroscience & …, 2020 - Elsevier
This systematic review examines the genetic and epigenetic factors associated with resting-
state functional connectivity (RSFC) in healthy human adult brains across the lifespan, with a …

Neural complexity as a potential translational biomarker for psychosis

B Hager, AC Yang, R Brady, S Meda… - Journal of affective …, 2017 - Elsevier
Background The adaptability of the human brain to the constantly changing environment is
reduced in patients with psychotic disorders, leading to impaired cognitive functions. Brain …