RNA modifications in cancer
Q Tang, L Li, Y Wang, P Wu, X Hou, J Ouyang… - British journal of …, 2023 - nature.com
Currently, more than 170 modifications have been identified on RNA. Among these RNA
modifications, various methylations account for two-thirds of total cases and exist on almost …
modifications, various methylations account for two-thirds of total cases and exist on almost …
Deciphering epitranscriptome: modification of mRNA bases provides a new perspective for post-transcriptional regulation of gene expression
S Kumar, T Mohapatra - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Gene regulation depends on dynamic and reversibly modifiable biological and chemical
information in the epigenome/epitranscriptome. Accumulating evidence suggests that …
information in the epigenome/epitranscriptome. Accumulating evidence suggests that …
The dynamic RNA modification 5‐methylcytosine and its emerging role as an epitranscriptomic mark
L Trixl, A Lusser - Wiley Interdisciplinary Reviews: RNA, 2019 - Wiley Online Library
It is a well‐known fact that RNA is the target of a plethora of modifications which currently
amount to over a hundred. The vast majority of these modifications was observed in the two …
amount to over a hundred. The vast majority of these modifications was observed in the two …
The integral role of RNA in stress granule formation and function
D Campos-Melo, ZCE Hawley… - Frontiers in Cell and …, 2021 - frontiersin.org
Stress granules (SGs) are phase-separated, membraneless, cytoplasmic ribonucleoprotein
(RNP) assemblies whose primary function is to promote cell survival by condensing …
(RNP) assemblies whose primary function is to promote cell survival by condensing …
Detection technologies for RNA modifications
Y Zhang, L Lu, X Li - Experimental & Molecular Medicine, 2022 - nature.com
To date, more than 170 chemical modifications have been characterized in RNA, providing a
new layer of gene expression regulation termed the 'epitranscriptome'. RNA modification …
new layer of gene expression regulation termed the 'epitranscriptome'. RNA modification …
RNA methylations in human cancers
RNA methylations, as the prevalent post-transcriptional modifications, are critical in
regulating various biological processes, such as RNA transcription, splicing, structure …
regulating various biological processes, such as RNA transcription, splicing, structure …
[HTML][HTML] The role of RNA m5C modification in cancer metastasis
Q Zhang, F Liu, W Chen, H Miao, H Liang… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Epigenetic modification plays a crucial regulatory role in the biological processes of
eukaryotic cells. The recent characterization of DNA and RNA methylation is still ongoing …
eukaryotic cells. The recent characterization of DNA and RNA methylation is still ongoing …
The epigenetic implication in coronavirus infection and therapy
Epigenetics is a relatively new field of science that studies the genetic and non-genetic
aspects related to heritable phenotypic changes, frequently caused by environmental and …
aspects related to heritable phenotypic changes, frequently caused by environmental and …
[HTML][HTML] m1A regulated genes modulate PI3K/AKT/mTOR and ErbB pathways in gastrointestinal cancer
BACKGROUND: Gene expression can be posttranscriptionally regulated by a complex
network of proteins. N1-methyladenosine (m1A) is a newly validated RNA modification …
network of proteins. N1-methyladenosine (m1A) is a newly validated RNA modification …
Roles of RNA modifications in diverse cellular functions
Chemical modifications of RNA molecules regulate both RNA metabolism and fate. The
deposition and function of these modifications are mediated by the actions of writer, reader …
deposition and function of these modifications are mediated by the actions of writer, reader …