Diagnosis and treatment of idiopathic normal pressure hydrocephalus

MA Williams, J Malm - Continuum: Lifelong Learning in Neurology, 2016 - journals.lww.com
Abstract Purpose of Review: This article provides neurologists with a pragmatic approach to
the diagnosis and treatment of idiopathic normal pressure hydrocephalus (iNPH), including …

Outcomes and complications of different surgical treatments for idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis

E Giordan, G Palandri, G Lanzino, MH Murad… - Journal of …, 2018 - thejns.org
OBJECTIVE Different CSF diversion procedures (ventriculoperitoneal, ventriculoatrial, and
lumboperitoneal shunting) have been utilized for the treatment of idiopathic normal pressure …

Prevalence of idiopathic normal pressure hydrocephalus: a prospective, population-based study

J Andersson, M Rosell, K Kockum, O Lilja-Lund… - PloS one, 2019 - journals.plos.org
Background Idiopathic normal pressure hydrocephalus (iNPH) causing gait impairment,
dementia and urinary incontinence among the elderly, is probably under-diagnosed and …

Lumboperitoneal shunt surgery for idiopathic normal pressure hydrocephalus (SINPHONI-2): an open-label randomised trial

H Kazui, M Miyajima, E Mori, M Ishikawa - The Lancet Neurology, 2015 - thelancet.com
Background Lumboperitoneal shunt surgery has the potential to alleviate symptoms of
normal pressure hydrocephalus but the benefits of such surgery have not been tested in a …

Noninvasive assessment of glymphatic dysfunction in idiopathic normal pressure hydrocephalus with diffusion tensor imaging

C Georgiopoulos, A Tisell, RT Holmgren… - Journal of …, 2023 - thejns.org
OBJECTIVE Diffusion tensor imaging (DTI) along the perivascular space (ALPS)(DTI-ALPS)—
by calculating the ALPS index, a ratio accentuating water diffusion in the perivascular space …

Normal pressure hydrocephalus—an overview of pathophysiological mechanisms and diagnostic procedures

P Skalický, A Mládek, A Vlasák, P De Lacy, V Beneš… - Neurosurgical …, 2020 - Springer
Normal pressure hydrocephalus (NPH) is an important differential diagnosis of
neurodegenerative diseases. The prevalence of dementia is increasing in line with the …

Epidemiology of idiopathic normal pressure hydrocephalus: a systematic review of the literature

R Martín-Láez, H Caballero-Arzapalo… - World neurosurgery, 2015 - Elsevier
Background Idiopathic normal pressure hydrocephalus (iNPH) is an important cause of gait
disturbance and cognitive impairment in elderly adults. However, the epidemiology of iNPH …

Regulation of brain fluid volumes and pressures: basic principles, intracranial hypertension, ventriculomegaly and hydrocephalus

SB Hladky, MA Barrand - Fluids and Barriers of the CNS, 2024 - Springer
The principles of cerebrospinal fluid (CSF) production, circulation and outflow and regulation
of fluid volumes and pressures in the normal brain are summarised. Abnormalities in these …

Neuroimaging in dementia

AM Staffaroni, FM Elahi, D McDermott… - Seminars in …, 2017 - thieme-connect.com
Although the diagnosis of dementia still is primarily based on clinical criteria, neuroimaging
is playing an increasingly important role. This is in large part due to advances in techniques …

Radiological predictors of shunt response in the diagnosis and treatment of idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis

SG Thavarajasingam, M El-Khatib, K Vemulapalli… - Acta …, 2023 - Springer
Background Patients with the dementia subtype idiopathic normal pressure hydrocephalus
(iNPH) may improve clinically following cerebrospinal fluid (CSF) diversion (shunt) surgery …