Fitness costs of plasmids: a limit to plasmid transmission
Plasmids mediate the horizontal transmission of genetic information between bacteria,
facilitating their adaptation to multiple environmental conditions. An especially important …
facilitating their adaptation to multiple environmental conditions. An especially important …
Mobility of plasmids
Plasmids are key vectors of horizontal gene transfer and essential genetic engineering tools.
They code for genes involved in many aspects of microbial biology, including detoxication …
They code for genes involved in many aspects of microbial biology, including detoxication …
CRISPR-Cas-based antimicrobials: design, challenges, and bacterial mechanisms of resistance
The emergence of antibiotic-resistant bacterial strains is a source of public health concern
across the globe. As the discovery of new conventional antibiotics has stalled significantly …
across the globe. As the discovery of new conventional antibiotics has stalled significantly …
Plasmid-mediated horizontal gene transfer is a coevolutionary process
Conjugative plasmids are key agents of horizontal gene transfer (HGT) that accelerate
bacterial adaptation by vectoring ecologically important traits between strains and species …
bacterial adaptation by vectoring ecologically important traits between strains and species …
Positive selection and compensatory adaptation interact to stabilize non-transmissible plasmids
Plasmids are important drivers of bacterial evolution, but it is challenging to understand how
plasmids persist over the long term because plasmid carriage is costly. Classical models …
plasmids persist over the long term because plasmid carriage is costly. Classical models …
Plasmid transfer in biofilms: a perspective on limitations and opportunities
Biofilms dominate microbial life, and their importance for human health and the environment
can no longer be dismissed. Nevertheless many of the processes governing this form of …
can no longer be dismissed. Nevertheless many of the processes governing this form of …
Source–sink plasmid transfer dynamics maintain gene mobility in soil bacterial communities
Horizontal gene transfer is a fundamental process in bacterial evolution that can accelerate
adaptation via the sharing of genes between lineages. Conjugative plasmids are the …
adaptation via the sharing of genes between lineages. Conjugative plasmids are the …
Identification of bacterial plasmids based on mobility and plasmid population biology
MP Garcillán-Barcia, A Alvarado… - FEMS microbiology …, 2011 - academic.oup.com
Plasmids contain a backbone of core genes that remains relatively stable for long
evolutionary periods, making sense to speak about plasmid species. The identification and …
evolutionary periods, making sense to speak about plasmid species. The identification and …
Cell-to-cell bacterial interactions promoted by drier conditions on soil surfaces
Bacterial cell-to-cell interactions are in the core of evolutionary and ecological processes in
soil and other environments. Under most conditions, natural soils are unsaturated where the …
soil and other environments. Under most conditions, natural soils are unsaturated where the …
Mathematical models of plasmid population dynamics
With plasmid-mediated antibiotic resistance thriving and threatening to become a serious
public health problem, it is paramount to increase our understanding of the forces that …
public health problem, it is paramount to increase our understanding of the forces that …