Does reduced MHC diversity decrease viability of vertebrate populations?
Loss of genetic variation may render populations more vulnerable to pathogens due to
inbreeding depression and depletion of variation in genes responsible for immunity against …
inbreeding depression and depletion of variation in genes responsible for immunity against …
Methods for MHC genoty** in non‐model vertebrates
W Babik - Molecular ecology resources, 2010 - Wiley Online Library
Genes of the major histocompatibility complex (MHC) are considered a paradigm of
adaptive evolution at the molecular level and as such are frequently investigated by …
adaptive evolution at the molecular level and as such are frequently investigated by …
[PDF][PDF] Population and distribution of Eurasian beaver (Castor fiber)
A fter being reduced to about 1,200 anim als in eight isolated populations by the beginning
of the 20th century, Eurasian beavers (Castor fiber) have powerfully recovered in range and …
of the 20th century, Eurasian beavers (Castor fiber) have powerfully recovered in range and …
[LLIBRE][B] Evolutionary conservation genetics
J Höglund - 2009 - books.google.com
Conservation genetics focuses on understanding the role and requirement of genetic
variation for population persistence. However, considerable debate now surrounds the role …
variation for population persistence. However, considerable debate now surrounds the role …
Effects of an MHC‐DRB genotype and allele number on the load of gut parasites in the bank vole Myodes glareolus
The major histocompatibility complex (MHC) genes code for the proteins responsible for
pathogen recognition. The MHC class II DRB gene is multiplicated in the bank vole, Myodes …
pathogen recognition. The MHC class II DRB gene is multiplicated in the bank vole, Myodes …
New generation sequencers as a tool for genoty** of highly polymorphic multilocus MHC system
Accurate genoty** of complex systems, such as the major histocompatibility complex
(MHC) often requires simultaneous analysis of multiple co‐amplifying loci. Here we explore …
(MHC) often requires simultaneous analysis of multiple co‐amplifying loci. Here we explore …
Cheetah paradigm revisited: MHC diversity in the world's largest free-ranging population
A Castro-Prieto, B Wachter… - Molecular biology and …, 2011 - academic.oup.com
For more than two decades, the cheetah (Acinonyx jubatus) has been considered a
paradigm of disease vulnerability associated with low genetic diversity, particularly at the …
paradigm of disease vulnerability associated with low genetic diversity, particularly at the …
MHC diversity in bottlenecked populations: a simulation model
The depletion of variation at MHC loci, which play a crucial role in pathogen recognition, has
been postulated to be one of important extinction risk factors for endangered populations …
been postulated to be one of important extinction risk factors for endangered populations …
Low MHC variation in the endangered Galápagos penguin (Spheniscus mendiculus)
JL Bollmer, FH Vargas, PG Parker - Immunogenetics, 2007 - Springer
The major histocompatibility complex (MHC) is one of the most polymorphic regions of the
genome, likely due to balancing selection acting to maintain alleles over time. Lack of MHC …
genome, likely due to balancing selection acting to maintain alleles over time. Lack of MHC …
Coevolutionary relationship between helminth diversity and MHC class II polymorphism in rodents
Parasite‐mediated selection on major histocompatibility complex (MHC) genes has mainly
been explored at the intraspecific level, although many molecular studies have revealed …
been explored at the intraspecific level, although many molecular studies have revealed …