NLRP3 inflammasome at the interface of inflammation, endothelial dysfunction, and type 2 diabetes
IM Gora, A Ciechanowska, P Ladyzynski - Cells, 2021 - mdpi.com
Type 2 diabetes mellitus (T2DM), accounting for 90–95% cases of diabetes, is characterized
by chronic inflammation. The mechanisms that control inflammation activation in T2DM are …
by chronic inflammation. The mechanisms that control inflammation activation in T2DM are …
Does a strict glycemic control during acute coronary syndrome play a cardioprotective effect? Pathophysiology and clinical evidence
A hyperglycemic state, also in non-diabetic subjects, may be associated with acute coronary
syndrome (ACS). Aim of this review is to describe the pathophysiologic association between …
syndrome (ACS). Aim of this review is to describe the pathophysiologic association between …
HDL in the 21st century: a multifunctional roadmap for future HDL research
A Rohatgi, M Westerterp, A Von Eckardstein… - Circulation, 2021 - Am Heart Assoc
Low high-density lipoprotein cholesterol (HDL-C) characterizes an atherogenic dyslipidemia
that reflects adverse lifestyle choices, impaired metabolism, and increased cardiovascular …
that reflects adverse lifestyle choices, impaired metabolism, and increased cardiovascular …
Cancer-cell-secreted extracellular vesicles suppress insulin secretion through miR-122 to impair systemic glucose homeostasis and contribute to tumour growth
Epidemiological studies demonstrate an association between breast cancer (BC) and
systemic dysregulation of glucose metabolism. However, how BC influences glucose …
systemic dysregulation of glucose metabolism. However, how BC influences glucose …
Retinal and circulating mi RNA expression patterns in diabetic retinopathy: An in silico and in vivo approach
CBM Platania, R Maisto, MC Trotta… - British journal of …, 2019 - Wiley Online Library
Background and Purpose Diabetic retinopathy, a secondary complication of diabetes
mellitus, can lead to irreversible vision loss. Currently, no treatment is approved for early …
mellitus, can lead to irreversible vision loss. Currently, no treatment is approved for early …
Role of flow-sensitive microRNAs and long noncoding RNAs in vascular dysfunction and atherosclerosis
Atherosclerosis is the primary underlying cause of myocardial infarction, ischemic stroke,
and peripheral artery disease. The disease preferentially occurs in arterial regions exposed …
and peripheral artery disease. The disease preferentially occurs in arterial regions exposed …
Role of microRNA in endothelial dysfunction and hypertension
Abstract Purpose of Review Hypertension is either a cause or a consequence of the
endothelial dysfunction and a major risk factor for cardiovascular disease (CVD). In vitro and …
endothelial dysfunction and a major risk factor for cardiovascular disease (CVD). In vitro and …
Phenolic compounds exerting lipid-regulatory, anti-inflammatory and epigenetic effects as complementary treatments in cardiovascular diseases
Atherosclerosis is the main process behind cardiovascular diseases (CVD), maladies which
continue to be responsible for up to 70% of death worldwide. Despite the ongoing …
continue to be responsible for up to 70% of death worldwide. Despite the ongoing …
Circulating miRNA profiles associated with hyperglycemia in patients with type 1 diabetes
We investigated plasma microRNA (miRNA) profiles associated with variation of
hyperglycemia, measured as hemoglobin A1c (HbA1c), in two panels of patients with type 1 …
hyperglycemia, measured as hemoglobin A1c (HbA1c), in two panels of patients with type 1 …
Microvesicle-associated and circulating microRNAs in diabetic dyslipidemia: miR-218, miR-132, miR-143, and miR-21, miR-122, miR-155 have biomarker potential
Abstract Background Circulating MicroRNAs (miRNAs) carried by microvesicles (MVs) have
various physiological and pathological functions by post-transcriptional regulation of gene …
various physiological and pathological functions by post-transcriptional regulation of gene …