Acyl-homoserine lactone-based quorum sensing and quorum quenching hold promise to determine the performance of biological wastewater treatments: an overview

J Huang, Y Shi, G Zeng, Y Gu, G Chen, L Shi, Y Hu… - Chemosphere, 2016 - Elsevier
Quorum sensing (QS) is a communication process between cells, in which bacteria secrete
and sense the specific chemicals, and regulate gene expression in response to population …

Peptides as Quorum Sensing Molecules: Measurement Techniques and Obtained Levels In vitro and In vivo

F Verbeke, S De Craemer, N Debunne… - Frontiers in …, 2017 - frontiersin.org
The expression of certain bacterial genes is regulated in a cell-density dependent way, a
phenomenon called quorum sensing. Both Gram-negative and Gram-positive bacteria use …

Biocontrol of Bacterial Leaf Blight of Rice and Profiling of Secondary Metabolites Produced by Rhizospheric Pseudomonas aeruginosa BRp3

S Yasmin, FY Hafeez, MS Mirza, M Rasul… - Frontiers in …, 2017 - frontiersin.org
Xanthomonas oryzae pv. oryzae (Xoo) is widely prevalent and causes Bacterial Leaf Blight
(BLB) in Basmati rice grown in different areas of Pakistan. There is a need to use …

Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa

SR Borgert, S Henke, F Witzgall, S Schmelz… - Nature …, 2022 - nature.com
Pseudomonas aeruginosa is a major cause of nosocomial infections and also leads to
severe exacerbations in cystic fibrosis or chronic obstructive pulmonary disease. Three …

A Cell-Free Biosensor for Detecting Quorum Sensing Molecules in P. aeruginosa-Infected Respiratory Samples

KY Wen, L Cameron, J Chappell, K Jensen… - ACS synthetic …, 2017 - ACS Publications
Synthetic biology designed cell-free biosensors are a promising new tool for the detection of
clinically relevant biomarkers in infectious diseases. Here, we report that a modular DNA …

Exploring an Efficient and Eco-Friendly Signaling Molecule and Its Quorum Quenching Ability for Controlling Microcystis Blooms

G Yan, L Fu, H Ming, C Chen… - Environmental Science & …, 2023 - ACS Publications
Globally, cyanobacterial blooms have become serious problems in eutrophic water. Most
previous studies have focused on environmental factors but have neglected the role of …

Unravelling the Genome-Wide Contributions of Specific 2-Alkyl-4-Quinolones and PqsE to Quorum Sensing in Pseudomonas aeruginosa

G Rampioni, M Falcone, S Heeb, E Frangipani… - PLoS …, 2016 - journals.plos.org
The pqs quorum sensing (QS) system is crucial for Pseudomonas aeruginosa virulence both
in vitro and in animal models of infection and is considered an ideal target for the …

Bacteria-Host Crosstalk: Sensing of the Quorum in the Context of Pseudomonas aeruginosa Infections

MV Turkina, E Vikström - Journal of innate immunity, 2019 - karger.com
Cell-to-cell signaling via small molecules is an essential process to coordinate behavior in
single species within a community, and also across kingdoms. In this review, we discuss the …

Non-antibiotic quorum sensing inhibitors acting against N-acyl homoserine lactone synthase as druggable target

CY Chang, T Krishnan, H Wang, Y Chen, WF Yin… - Scientific reports, 2014 - nature.com
Abstract N-acylhomoserine lactone (AHL)-based quorum sensing (QS) is important for the
regulation of proteobacterial virulence determinants. Thus, the inhibition of AHL synthases …

Identification of FDA-Approved Drugs as Antivirulence Agents Targeting the pqs Quorum-Sensing System of Pseudomonas aeruginosa

F D'Angelo, V Baldelli, N Halliday… - Antimicrobial Agents …, 2018 - Am Soc Microbiol
The long-term use of antibiotics has led to the emergence of multidrug-resistant bacteria. A
promising strategy to combat bacterial infections aims at hampering their adaptability to the …