[HTML][HTML] The anticancer mechanism of action of selected polyphenols in triple-negative breast cancer (TNBC)

R Farghadani, R Naidu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Breast cancer is a leadingcause of cancer-related deaths in women globally, with triple-
negative breast cancer (TNBC) being an aggressive subtype that lacks targeted therapies …

Targets involved in the anti-cancer activity of quercetin in breast, colorectal and liver neoplasms

A Maugeri, A Calderaro, GT Patanè, M Navarra… - International Journal of …, 2023 - mdpi.com
Phytochemicals have long been effective partners in the fight against several diseases,
including cancer. Among these, flavonoids are valuable allies for both cancer prevention …

[HTML][HTML] Fisetin, a potent anticancer flavonol exhibiting cytotoxic activity against neoplastic malignant cells and cancerous conditions: A sco**, comprehensive …

R Kubina, K Krzykawski, A Kabała-Dzik, RD Wojtyczka… - Nutrients, 2022 - mdpi.com
Diet plays a crucial role in homeostasis maintenance. Plants and spices containing
flavonoids have been widely used in traditional medicine for thousands of years. Flavonols …

[HTML][HTML] Breast tumor-on-chip models: From disease modeling to personalized drug screening

B Subia, UR Dahiya, S Mishra, J Ayache… - Journal of Controlled …, 2021 - Elsevier
Breast cancer is one of the leading causes of mortality worldwide being the most common
cancer among women. Despite the significant progress obtained during the past years in the …

Prodigiosin/PU-H71 as a novel potential combined therapy for triple negative breast cancer (TNBC): preclinical insights

MM Anwar, M Shalaby, AM Embaby, H Saeed… - Scientific Reports, 2020 - nature.com
Prodigiosin, a secondary metabolite red pigment produced by Serratia marcescens, has an
interesting apoptotic efficacy against cancer cell lines with low or no toxicity on normal cells …

Cancer chemopreventive role of fisetin: Regulation of cell signaling pathways in different cancers

AA Farooqi, H Naureen, R Zahid, L Youssef… - Pharmacological …, 2021 - Elsevier
It is becoming progressively more understandable that pharmaceutical targeting of drug-
resistant cancers is challenging because of intra-and inter-tumor heterogeneity …

Targeted fisetin-encapsulated β-cyclodextrin nanosponges for breast cancer

AR Aboushanab, RM El-Moslemany, AH El-Kamel… - Pharmaceutics, 2023 - mdpi.com
Fisetin (FS) is considered a safer phytomedicine alternative to conventional
chemotherapeutics for breast cancer treatment. Despite its surpassing therapeutic potential …

[HTML][HTML] Heracleum persicum Essential Oil Nanoemulsion: A Nanocarrier System for the Delivery of Promising Anticancer and Antioxidant Bioactive Agents

SG Bashlouei, E Karimi, M Zareian, E Oskoueian… - Antioxidants, 2022 - mdpi.com
Essential oils are important compounds for the prevention and/or treatment of various
diseases in which solubility and bio-accessibility can be improved by nanoemulsion …

Quercetin impairs HuR-driven progression and migration of triple negative breast cancer (TNBC) cells

SM Umar, S Patra, A Kashyap, A Dev JR… - Nutrition and …, 2022 - Taylor & Francis
In the present study, we have explored the prognostic value of HuR gene as well as protein
in breast cancers. Furthermore, we have also investigated the HuR therapeutic relevance in …

Role of Fisetin in selected malignant neoplasms in women

A Markowska, M Antoszczak, K Kacprzak, J Markowska… - Nutrients, 2023 - mdpi.com
A promising therapeutic window and cost-effectiveness are just two of the potential
advantages of using naturally derived drugs. Fisetin (3, 3′, 4′, 7-tetrahydroxyflavone) is a …