A framework for understanding the functions of biomolecular condensates across scales
AS Lyon, WB Peeples, MK Rosen - Nature Reviews Molecular Cell …, 2021 - nature.com
Biomolecular condensates are found throughout eukaryotic cells, including in the nucleus, in
the cytoplasm and on membranes. They are also implicated in a wide range of cellular …
the cytoplasm and on membranes. They are also implicated in a wide range of cellular …
Physical principles underlying the complex biology of intracellular phase transitions
Many biomolecular condensates appear to form via spontaneous or driven processes that
have the hallmarks of intracellular phase transitions. This suggests that a common …
have the hallmarks of intracellular phase transitions. This suggests that a common …
Protein cages: from fundamentals to advanced applications
Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …
Conformational dynamics of intrinsically disordered proteins regulate biomolecular condensate chemistry
Motions in biomolecules are critical for biochemical reactions. In cells, many biochemical
reactions are executed inside of biomolecular condensates formed by ultradynamic …
reactions are executed inside of biomolecular condensates formed by ultradynamic …
The emergence of phase separation as an organizing principle in bacteria
Recent investigations in bacteria suggest that membraneless organelles play a crucial role
in the subcellular organization of bacterial cells. However, the biochemical functions and …
in the subcellular organization of bacterial cells. However, the biochemical functions and …
Liquid-liquid phase separation of RBGD2/4 is required for heat stress resistance in Arabidopsis
S Zhu, J Gu, J Yao, Y Li, Z Zhang, W **a, Z Wang… - Developmental Cell, 2022 - cell.com
As sessile organisms, plants are highly sensitive to environmental stresses. In response to
stresses, globally repressed translation initiation leads to stress granule (SG) formation …
stresses, globally repressed translation initiation leads to stress granule (SG) formation …
Formation and function of bacterial organelles
Advances in imaging technologies have revealed that many bacteria possess organelles
with a proteomically defined lumen and a macromolecular boundary. Some are bound by a …
with a proteomically defined lumen and a macromolecular boundary. Some are bound by a …
Rubisco function, evolution, and engineering
Carbon fixation is the process by which CO2 is converted from a gas into biomass. The
Calvin–Benson–Bassham cycle (CBB) is the dominant carbon-consuming pathway on …
Calvin–Benson–Bassham cycle (CBB) is the dominant carbon-consuming pathway on …
Identification of a carbonic anhydrase–Rubisco complex within the alpha-carboxysome
Carboxysomes are proteinaceous organelles that encapsulate key enzymes of CO2 fixation—
Rubisco and carbonic anhydrase—and are the centerpiece of the bacterial CO2 …
Rubisco and carbonic anhydrase—and are the centerpiece of the bacterial CO2 …
Structure and assembly of cargo Rubisco in two native α-carboxysomes
Carboxysomes are a family of bacterial microcompartments in cyanobacteria and
chemoautotrophs. They encapsulate Ribulose 1, 5-bisphosphate carboxylase/oxygenase …
chemoautotrophs. They encapsulate Ribulose 1, 5-bisphosphate carboxylase/oxygenase …