Summary Background Data Women who are at high risk for breast cancer have a variety of
options available to them, including watchful waiting, prophylactic surgery, and …

Breast cancer in men is a rare disease, accounting for∼ 1% of all breast cancer cases.
Although the epidemiologic literature regarding female breast cancer is extensive, relatively …

The contribution of BRCA1 and BRCA2 to inherited breast cancer was assessed by linkage
and mutation analysis in 237 families, each with at least four cases of breast cancer …

PURPOSE: To compare magnetic resonance (MR) imaging with conventional imaging in
screening high-risk women. MATERIALS AND METHODS: This prospective trial included …

Purpose: To prospectively compare clinical breast examination (CBE), mammography,
ultrasonography (US), and contrast material–enhanced magnetic resonance (MR) imaging …

In 1992, the Musee de L'Homme in Paris presented a natural history exhibit entitled" Tous
Parents, Tous Dif-ferents," a beautiful scientific and artistic exploration of human evolution …

PURPOSE Previous studies of mutations in BRCA1 or BRCA2 have used detection methods
that may underestimate the actual frequency of mutations and have analyzed women using …

This review focuses on genes other than the high penetrance genes BRCA1 and BRCA2
that are involved in breast cancer susceptibility. The goal of this review is the discovery of …

Context.—Previous studies of BRCA1 mutation prevalence have been based on high-risk
groups, yielding estimates that do not reflect the experience of the general population of US …

This well-organized and clearly written text has a unique focus on methods of identifying the
joint effects of genes and environment on disease patterns. It follows the natural sequence of …