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Management of severe perioperative bleeding: guidelines from the European Society of Anaesthesiology
The aims of severe perioperative bleeding management are three-fold. First, preoperative
identification by anamesis and laboratory testing of those patients for whom the …
identification by anamesis and laboratory testing of those patients for whom the …
[HTML][HTML] Platelet function analyzer (PFA)‐100® closure time in the evaluation of platelet disorders and platelet function
Summary Background: Closure time (CT), measured by platelet function analyzer (PFA‐
100®) device, is now available to the clinical laboratory as a possible alternative or …
100®) device, is now available to the clinical laboratory as a possible alternative or …
Stop** vs. continuing aspirin before coronary artery surgery
Background Most patients with coronary artery disease receive aspirin for primary or
secondary prevention of myocardial infarction, stroke, and death. Aspirin poses a risk of …
secondary prevention of myocardial infarction, stroke, and death. Aspirin poses a risk of …
Peri-operative management of antiplatelet therapy in patients with coronary artery disease
An increasing number of patients suffering from cardiovascular disease, especially coronary
artery disease (CAD), are treated with aspirin and/or clopidogrel for the prevention of major …
artery disease (CAD), are treated with aspirin and/or clopidogrel for the prevention of major …
A multiple dose study of prasugrel (CS‐747), a novel thienopyridine P2Y12 inhibitor, compared with clopidogrel in healthy humans
JA Jakubowski, N Matsushima, F Asai… - British journal of …, 2007 - Wiley Online Library
Aims This double‐blind, placebo‐controlled trial was designed to evaluate the
pharmacodynamics, pharmacokinetics, safety, and tolerability of prasugrel (CS‐747 …
pharmacodynamics, pharmacokinetics, safety, and tolerability of prasugrel (CS‐747 …
Acquired disorders of platelet function
BA Konkle - Hematology 2010, the American Society of …, 2011 - ashpublications.org
Platelet dysfunction is commonly acquired due to medications, procedures, medical
conditions, and underlying hematologic disease. These issues are presented, the data …
conditions, and underlying hematologic disease. These issues are presented, the data …
Perioperative antiplatelet therapy
PG Chassot, C Marcucci, A Delabays… - American family …, 2010 - aafp.org
Aspirin is recommended as a lifelong therapy that should never be interrupted for patients
with cardiovascular disease. Clopidogrel therapy is mandatory for six weeks after placement …
with cardiovascular disease. Clopidogrel therapy is mandatory for six weeks after placement …
Whole blood multiple electrode aggregometry is a reliable point-of-care test of aspirin-induced platelet dysfunction
C Jámbor, CF Weber, K Gerhardt, W Dietrich… - Anesthesia & …, 2009 - journals.lww.com
BACKGROUND: Aspirin is one of the most commonly ingested over-the-counter drugs. In
addition to its analgesic and antiinflammatory actions, it also potently inhibits platelet …
addition to its analgesic and antiinflammatory actions, it also potently inhibits platelet …
Does antiplatelet therapy affect outcomes of patients receiving abdominal laparoscopic surgery? Lessons from more than 1,000 laparoscopic operations in a single …
T Fujikawa, A Tanaka, T Abe, Y Yoshimoto… - Journal of the American …, 2013 - Elsevier
Background The effect of antiplatelet therapy (APT) on surgical blood loss and perioperative
complications in patients receiving abdominal laparoscopic surgery still remains unclear …
complications in patients receiving abdominal laparoscopic surgery still remains unclear …
[HTML][HTML] Recovery time of platelet function after aspirin withdrawal
J Lee, JK Kim, JH Kim, T Dunuu, SH Park… - Current Therapeutic …, 2014 - Elsevier
Introduction Inappropriate antiplatelet therapy discontinuation increases the risk of
thrombotic complications and bleeding after dental procedures. To determine the platelet …
thrombotic complications and bleeding after dental procedures. To determine the platelet …