In recent years, the continuous occurrence of multi-drug resistance in the clinic has made
people pay more attention to the transporter. Changes in the expression and activity of …

The precision, minimal invasiveness, and integration of diagnosis and treatment are critical
factors for tumor treatment at the present. Although nanomedicine has shown the potential in …

RNA therapeutics (eg siRNA, oligonucleotides, mRNA, etc.) show great potential for the
treatment of a myriad of diseases. However, to reach their site of action in the cytosol or …

Inorganic nanoparticles (NPs) and nanocomposites (NCs) generally possess versatile
properties, that is, good specific surface area (SSA), magnetism, easy functionalization with …

Cancer still represents a leading threat to human health worldwide. The effective usage of
anti-cancer drugs can reduce patients' clinical symptoms and extend life-span survival time …

Significance: Nanomedicine is an application of nanotechnology that provides solutions to
unmet medical challenges. The unique features of nanoparticles, such as their small size …

Non‐small cell lung cancer (NSCLC) is the primary cause of cancer death worldwide.
Despite developments in chemotherapy and targeted therapies, the 5‐year survival rate has …

We introduce a toehold-mediated strand displacement strategy for regulated shape-
switching of nucleic acid nanoparticles (NANPs) enabling their sequential transformation …

Research on siRNA is increasing due to its wide applicability as a therapeutic agent in
irreversible medical conditions. siRNA inhibits expression of the specific gene after its …

Background Myocardial dysfunction played a vital role in organ damage after sepsis. Fluid
resuscitation was the essential treatment in which Lactate Ringer's solution (LR) was …