[HTML][HTML] Small heat shock proteins: role in cellular functions and pathology
Small heat shock proteins (sHsps) are conserved across species and are important in stress
tolerance. Many sHsps exhibit chaperone-like activity in preventing aggregation of target …
tolerance. Many sHsps exhibit chaperone-like activity in preventing aggregation of target …
GFAP in health and disease
Glial fibrillary acidic protein (GFAP) is the main intermediate filament protein in mature
astrocytes, but also an important component of the cytoskeleton in astrocytes during …
astrocytes, but also an important component of the cytoskeleton in astrocytes during …
'Hard'and 'soft'principles defining the structure, function and regulation of keratin intermediate filaments
PA Coulombe, MB Omary - Current opinion in cell biology, 2002 - Elsevier
Keratins make up the largest subgroup of intermediate filament proteins and represent the
most abundant proteins in epithelial cells. They exist as highly dynamic networks of …
most abundant proteins in epithelial cells. They exist as highly dynamic networks of …
Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy
OV Evgrafov, I Mersiyanova, J Irobi, L Van Den Bosch… - Nature …, 2004 - nature.com
Abstract Charcot-Marie-Tooth disease (CMT) is the most common inherited neuromuscular
disease and is characterized by considerable clinical and genetic heterogeneity. We …
disease and is characterized by considerable clinical and genetic heterogeneity. We …
[HTML][HTML] The growing world of small heat shock proteins: from structure to functions
Small heat shock proteins (sHSPs) are present in all kingdoms of life and play fundamental
roles in cell biology. sHSPs are key components of the cellular protein quality control …
roles in cell biology. sHSPs are key components of the cellular protein quality control …
Small heat shock proteins: molecular structure and chaperone function
Y Sun, TH MacRae - Cellular and Molecular Life Sciences CMLS, 2005 - Springer
Small heat shock proteins (sHSPs) associate with nuclei, cytoskeleton and membranes, and
as molecular chaperones they bind partially denatured proteins, thereby preventing …
as molecular chaperones they bind partially denatured proteins, thereby preventing …
Heat shock proteins and heat shock factor 1 in carcinogenesis and tumor development: an update
DR Ciocca, AP Arrigo, SK Calderwood - Archives of toxicology, 2013 - Springer
Heat shock proteins (HSP) are a subset of the molecular chaperones, best known for their
rapid and abundant induction by stress. HSP genes are activated at the transcriptional level …
rapid and abundant induction by stress. HSP genes are activated at the transcriptional level …
On the role of Hsp27 in regulating apoptosis
Heat shock proteins (Hsps) comprise several different families of proteins that are induced in
response to a wide variety of physiological and environmental insults. One such protein …
response to a wide variety of physiological and environmental insults. One such protein …
Structure and function of the small heat shock protein/α-crystallin family of molecular chaperones
R Van Montfort, C Slingsby, E Vierlingt - Advances in protein chemistry, 2001 - Elsevier
Publisher Summary The goal of this chapter is to clarify the diversity within the heat shock
proteins (sHsps) family and to describe evidence indicating that sHsps have many different …
proteins (sHsps) family and to describe evidence indicating that sHsps have many different …
Intermediate filaments take the heat as stress proteins
Intermediate filament (IF) proteins and heat shock proteins (HSPs) are large multimember
families that share several features, including protein abundance, significant upregulation in …
families that share several features, including protein abundance, significant upregulation in …