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The Hippo signalling pathway and its implications in human health and diseases
M Fu, Y Hu, T Lan, KL Guan, T Luo… - Signal transduction and …, 2022 - nature.com
As an evolutionarily conserved signalling network, the Hippo pathway plays a crucial role in
the regulation of numerous biological processes. Thus, substantial efforts have been made …
the regulation of numerous biological processes. Thus, substantial efforts have been made …
Cardiovascular disease in chronic kidney disease: pathophysiological insights and therapeutic options
J Jankowski, J Floege, D Fliser, M Böhm, N Marx - Circulation, 2021 - ahajournals.org
Patients with chronic kidney disease (CKD) exhibit an elevated cardiovascular risk
manifesting as coronary artery disease, heart failure, arrhythmias, and sudden cardiac …
manifesting as coronary artery disease, heart failure, arrhythmias, and sudden cardiac …
[HTML][HTML] Harmonizing acute and chronic kidney disease definition and classification: report of a Kidney Disease: Improving Global Outcomes (KDIGO) Consensus …
Kidney disease is an important public health problem. Both acute kidney injury (AKI) and
chronic kidney disease (CKD) have been well defined and classified leading to improved …
chronic kidney disease (CKD) have been well defined and classified leading to improved …
Inhibition of ACSS2-mediated histone crotonylation alleviates kidney fibrosis via IL-1β-dependent macrophage activation and tubular cell senescence
L Li, T **ang, J Guo, F Guo, Y Wu, H Feng, J Liu… - Nature …, 2024 - nature.com
Histone lysine crotonylation (Kcr), as a posttranslational modification, is widespread as
acetylation (Kac); however, its roles are largely unknown in kidney fibrosis. In this study, we …
acetylation (Kac); however, its roles are largely unknown in kidney fibrosis. In this study, we …
Kidney damage causally affects the brain cortical structure: a Mendelian randomization study
X Chen, J Kong, J Pan, K Huang, W Zhou, X Diao… - …, 2021 - thelancet.com
Background Alterations in the brain cortical structures of patients with chronic kidney
disease (CKD) have been reported; however, the cause has not been determined yet …
disease (CKD) have been reported; however, the cause has not been determined yet …
[HTML][HTML] Nomenclature for kidney function and disease: report of a Kidney Disease: Improving Global Outcomes (KDIGO) Consensus Conference
AS Levey, KU Eckardt, NM Dorman, SL Christiansen… - Kidney international, 2020 - Elsevier
The worldwide burden of kidney disease is rising, but public awareness remains limited,
underscoring the need for more effective communication by stakeholders in the kidney …
underscoring the need for more effective communication by stakeholders in the kidney …
A catalog of genetic loci associated with kidney function from analyses of a million individuals
Chronic kidney disease (CKD) is responsible for a public health burden with multi-systemic
complications. Through trans-ancestry meta-analysis of genome-wide association studies of …
complications. Through trans-ancestry meta-analysis of genome-wide association studies of …
NAFLD as a driver of chronic kidney disease
CD Byrne, G Targher - Journal of hepatology, 2020 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD) are worldwide
public health problems, affecting up to 25–30%(NAFLD), and up to 10–15%(CKD) of the …
public health problems, affecting up to 25–30%(NAFLD), and up to 10–15%(CKD) of the …
Chronic kidney disease
Chronic kidney disease (CKD) is defined by persistent urine abnormalities, structural
abnormalities or impaired excretory renal function suggestive of a loss of functional …
abnormalities or impaired excretory renal function suggestive of a loss of functional …
Workers' health and productivity under occupational heat strain: a systematic review and meta-analysis
Background Occupational heat strain (ie, the effect of environmental heat stress on the body)
directly threatens workers' ability to live healthy and productive lives. We estimated the …
directly threatens workers' ability to live healthy and productive lives. We estimated the …