Confocal microscopy for diagnosis and management of cutaneous malignancies: clinical impacts and innovation

MF Atak, B Farabi, C Navarrete-Dechent, G Rubinstein… - Diagnostics, 2023 - mdpi.com
Cutaneous malignancies are common malignancies worldwide, with rising incidence. Most
skin cancers, including melanoma, can be cured if diagnosed correctly at an early stage …

[HTML][HTML] Advances in landscape and related therapeutic targets of the prostate tumor microenvironment: Therapeutic targets of the prostate tumor microenvironment

D Li, W Xu, Y Chang, Y **ao, Y He… - Acta Biochimica et …, 2023 - ncbi.nlm.nih.gov
The distinct tumor microenvironment (TME) of prostate cancer (PCa), which promotes tumor
proliferation and progression, consists of various stromal cells, immune cells, and a dense …

The macrophage-associated prognostic gene ANXA5 promotes immunotherapy resistance in gastric cancer through angiogenesis

Z Hong, P Wen, K Wang, X Wei, W **e, S Rao, X Chen… - BMC cancer, 2024 - Springer
Gastric cancer (GC) remains a predominant form of malignant tumor globally, necessitating
innovative non-surgical therapeutic approaches. This investigation aimed to delineate the …

Dual-enzyme decorated semiconducting polymer nanoagents for second near-infrared photoactivatable ferroptosis-immunotherapy

Y Liu, R Lu, M Li, D Cheng, F Wang, X Ouyang… - Materials …, 2024 - pubs.rsc.org
Enzymes provide a class of potential options to treat cancer, while the precise regulation of
enzyme activities for effective and safe therapeutic actions has been poorly reported. Dual …

When inflammatory stressors dramatically change, disease phenotypes may transform between autoimmune hematopoietic failure and myeloid neoplasms

XC Zhao, B Ju, NN **u, XY Sun, FJ Meng - Frontiers in Immunology, 2024 - frontiersin.org
Aplastic anemia (AA) and hypoplastic myelodysplastic syndrome are paradigms of
autoimmune hematopoietic failure (AHF). Myelodysplastic syndrome and acute myeloid …

[HTML][HTML] Towards targeting endothelial Rap1B to overcome vascular immunosuppression in cancer

B Ghadrdoost Nakhchi, R Kosuru… - International Journal of …, 2024 - mdpi.com
The vascular endothelium, a specialized monolayer of endothelial cells (ECs), is crucial for
maintaining vascular homeostasis by controlling the passage of substances and cells. In the …

The road after cancer: biomaterials and tissue engineering approaches to mediate the tumor microenvironment post-cancer treatment

L Westwood, IJ Nixon, E Emmerson… - Frontiers in Biomaterials …, 2024 - frontiersin.org
Cancer affects tens of millions of the world's population each year with a stark mortality rate.
It is well established that in order to be effective in treating solid tumor cancers, the current …

Breaking the Tumor Chronic Inflammation Balance with a Programmable Release and Multi‐Stimulation Engineering Scaffold for Potent Immunotherapy

X Liang, X Li, R Wu, T He, F Liu, L Li… - Advanced …, 2024 - Wiley Online Library
Tumor‐associated chronic inflammation severely restricts the efficacy of immunotherapy in
cold tumors. Here, a programmable release hydrogel‐based engineering scaffold with multi …

Unveiling Major Histocompatibility Complex-mediated Pan-Cancer Immune Features by Integrated Single-Cell and Bulk RNA Sequencing

HR Feng, XN Shen, XM Zhu, WT Zhong, DX Zhu… - Cancer Letters, 2024 - Elsevier
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, yet persistent
challenges such as low response rate and significant heterogeneity necessitate attention …