MicroRNA
MicroRNAs (miRNAs) are small endogenous RNAs that regulate gene-expression
posttranscriptionally. MiRNA research in allergy is expanding because miRNAs are crucial …
posttranscriptionally. MiRNA research in allergy is expanding because miRNAs are crucial …
Endogenous microRNA sponges: evidence and controversy
The competitive endogenous RNA (ceRNA) hypothesis proposes that transcripts with
shared microRNA (miRNA) binding sites compete for post-transcriptional control. This …
shared microRNA (miRNA) binding sites compete for post-transcriptional control. This …
[HTML][HTML] Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis
SA Melo, H Sugimoto, JT O'Connell, N Kato… - Cancer cell, 2014 - cell.com
Exosomes are secreted by all cell types and contain proteins and nucleic acids. Here, we
report that breast cancer associated exosomes contain microRNAs (miRNAs) associated …
report that breast cancer associated exosomes contain microRNAs (miRNAs) associated …
Transfection types, methods and strategies: a technical review
Transfection is a modern and powerful method used to insert foreign nucleic acids into
eukaryotic cells. The ability to modify host cells' genetic content enables the broad …
eukaryotic cells. The ability to modify host cells' genetic content enables the broad …
MicroRNA delivery through nanoparticles
MicroRNAs (miRNAs) are attracting a growing interest in the scientific community due to
their central role in the etiology of major diseases. On the other hand, nanoparticle carriers …
their central role in the etiology of major diseases. On the other hand, nanoparticle carriers …
The regulatory role of microRNAs in breast cancer
HY Loh, BP Norman, KS Lai, NMANA Rahman… - International journal of …, 2019 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNA molecules which function as critical post-
transcriptional gene regulators of various biological functions. Generally, miRNAs negatively …
transcriptional gene regulators of various biological functions. Generally, miRNAs negatively …
Recent advances in microscale electroporation
Electroporation (EP) is a commonly used strategy to increase cell permeability for
intracellular cargo delivery or irreversible cell membrane disruption using electric fields. In …
intracellular cargo delivery or irreversible cell membrane disruption using electric fields. In …
Nucleic acid drugs: recent progress and future perspectives
X Sun, S Setrerrahmane, C Li, J Hu, H Xu - Signal Transduction and …, 2024 - nature.com
High efficacy, selectivity and cellular targeting of therapeutic agents has been an active area
of investigation for decades. Currently, most clinically approved therapeutics are small …
of investigation for decades. Currently, most clinically approved therapeutics are small …
Transfection of microRNA mimics should be used with caution
Transient transfection of chemically synthesized microRNA (miRNA) mimics is being used
extensively to study the functions and mechanisms of endogenous miRNAs. However, it …
extensively to study the functions and mechanisms of endogenous miRNAs. However, it …
Pancreatic cancer‐secreted miR‐155 implicates in the conversion from normal fibroblasts to cancer‐associated fibroblasts
W Pang, J Su, Y Wang, H Feng, X Dai, Y Yuan… - Cancer …, 2015 - Wiley Online Library
Cancer‐associated fibroblasts (CAF) are a major constituent of the pancreatic cancer
microenvironment and that the meaning is as intended. Pancreatic cancer cells can induce …
microenvironment and that the meaning is as intended. Pancreatic cancer cells can induce …