Pili Assembled by the Chaperone/Usher Pathway in Escherichia coli and Salmonella

GT Werneburg, DG Thanassi - EcoSal Plus, 2018 - Am Soc Microbiol
Gram-negative bacteria assemble a variety of surface structures, including the hair-like
organelles known as pili or fimbriae. Pili typically function in adhesion and mediate …

[HTML][HTML] The molecular dissection of the chaperone–usher pathway

S Geibel, G Waksman - Biochimica et Biophysica Acta (BBA)-Molecular …, 2014 - Elsevier
Secretion systems are specialized in transport of proteins, DNA or nutrients across the cell
envelope of bacteria and enable them to communicate with their environment. The …

The electrically conductive pili of Geobacter species are a recently evolved feature for extracellular electron transfer

DE Holmes, Y Dang, DJF Walker… - Microbial …, 2016 - microbiologyresearch.org
The electrically conductive pili (e-pili) of Geobactersulfurreducens have environmental and
practical significance because they can facilitate electron transfer to insoluble Fe (III) oxides; …

Broadly conserved roles of TMEM131 family proteins in intracellular collagen assembly and secretory cargo trafficking

Z Zhang, M Bai, GO Barbosa, A Chen, Y Wei, S Luo… - Science …, 2020 - science.org
Collagen is the most abundant protein in animals. Its dysregulation contributes to aging and
many human disorders, including pathological tissue fibrosis in major organs. How …

Molecular mechanism of bacterial type 1 and P pili assembly

A Busch, G Phan, G Waksman - … Transactions of the …, 2015 - royalsocietypublishing.org
The formation of adhesive surface structures called pili or fimbriae ('bacterial hair') is an
important contributor towards bacterial pathogenicity and persistence. To fight often chronic …

Functional analysis of Escherichia coli Yad fimbriae reveals their potential role in environmental persistence

F Larsonneur, FA Martin, A Mallet… - Environmental …, 2016 - Wiley Online Library
Initial adhesion of bacterial cells to surfaces or host tissues is a key step in colonisation and
biofilm formation processes, and is mediated by cell surface appendages. It was previously …

Structural basis of host recognition and biofilm formation by Salmonella Saf pili

L Zeng, L Zhang, P Wang, G Meng - Elife, 2017 - elifesciences.org
Pili are critical in host recognition, colonization and biofilm formation during bacterial
infection. Here, we report the crystal structures of SafD-dsc and SafD-SafA-SafA (SafDAA …

FimH and Type 1 Pili Mediated Tumor Cell Cytotoxicity by Uropathogenic Escherichia coli In Vitro

SR Van Eyssen, A Samarkina, O Isbilen, MS Zeden… - Pathogens, 2023 - mdpi.com
Uropathogenic Escherichia coli express hairlike proteinaceous surface projections, known
as chaperone–usher pathway (CUP) pili. Type 1 pili are CUP pili with well-established …

The Escherichia coli P and type 1 pilus assembly chaperones PapD and FimC are monomeric in solution

S Sarowar, OJ Hu, GT Werneburg… - Journal of …, 2016 - Am Soc Microbiol
The chaperone/usher pathway is used by Gram-negative bacteria to assemble adhesive
surface structures known as pili or fimbriae. Uropathogenic strains of Escherichia coli use …

Chaperone-tip adhesin complex is vital for synergistic activation of CFA/I fimbriae biogenesis

L He, H Wang, Y Liu, M Kang, T Li, C Li, A Tong… - PLoS …, 2020 - journals.plos.org
Colonization factor CFA/I defines the major adhesive fimbriae of enterotoxigenic Escherichia
coli and mediates bacterial attachment to host intestinal epithelial cells. The CFA/I fimbria …