Cell culture in microfluidic droplets
Cell manipulation in droplets has emerged as one of the great successes of microfluidic
technologies, with the development of single-cell screening. However, the droplet format has …
technologies, with the development of single-cell screening. However, the droplet format has …
Bioengineering approaches for the advanced organoid research
Recent advances in 3D cell culture technology have enabled scientists to generate stem cell
derived organoids that recapitulate the structural and functional characteristics of native …
derived organoids that recapitulate the structural and functional characteristics of native …
Recent methods of droplet microfluidics and their applications in spheroids and organoids
Y Wang, M Liu, Y Zhang, H Liu, L Han - Lab on a Chip, 2023 - pubs.rsc.org
Droplet microfluidic techniques have long been known as a high-throughput approach for
cell manipulation. The capacity to compartmentalize cells into picolitre droplets in …
cell manipulation. The capacity to compartmentalize cells into picolitre droplets in …
Microfluidic organoids-on-a-chip: Quantum leap in cancer research
Simple Summary Organoids, also known as self-organized 3D organ-like clusters, represent
almost a physiological system for studying cells, stem cells, tissues, and diseases, especially …
almost a physiological system for studying cells, stem cells, tissues, and diseases, especially …
Individual control and quantification of 3D spheroids in a high-density microfluidic droplet array
As three-dimensional cell culture formats gain in popularity, there emerges a need for tools
that produce vast amounts of data on individual cells within the spheroids or organoids …
that produce vast amounts of data on individual cells within the spheroids or organoids …
Recent Advances in Microfluidic Platforms for Programming Cell‐Based Living Materials
P Zhang, N Shao, L Qin - Advanced Materials, 2021 - Wiley Online Library
Cell‐based living materials, including single cells, cell‐laden fibers, cell sheets, organoids,
and organs, have attracted intensive interests owing to their widespread applications in …
and organs, have attracted intensive interests owing to their widespread applications in …
Three-dimensional Spheroid Culture Enhances Multipotent Differentiation and Stemness Capacities of Human Dental Pulp‐derived Mesenchymal Stem Cells by …
YH Chan, YC Lee, CY Hung, PJ Yang, PC Lai… - Stem Cell Reviews and …, 2021 - Springer
Abstract Background Three-dimensional (3D) culture of mesenchymal stem cells has
become an important research and development topic. However, comprehensive analysis of …
become an important research and development topic. However, comprehensive analysis of …
High resolution microfluidic assay and probabilistic modeling reveal cooperation between T cells in tumor killing
Cytotoxic T cells are important components of natural anti-tumor immunity and are
harnessed in tumor immunotherapies. Immune responses to tumors and immune therapy …
harnessed in tumor immunotherapies. Immune responses to tumors and immune therapy …
[HTML][HTML] Transient suppression of SUMOylation in embryonic stem cells generates embryo-like structures
Recent advances in synthetic embryology have opened new avenues for understanding the
complex events controlling mammalian peri-implantation development. Here, we show that …
complex events controlling mammalian peri-implantation development. Here, we show that …
[HTML][HTML] Combinatorial drug screening on 3D Ewing sarcoma spheroids using droplet-based microfluidics
R Fevre, G Mary, N Vertti-Quintero, A Durand… - Iscience, 2023 - cell.com
Culturing and screening cells in microfluidics, particularly in three-dimensional formats, has
the potential to impact diverse areas from fundamental biology to cancer precision medicine …
the potential to impact diverse areas from fundamental biology to cancer precision medicine …