HT receptors expressed throughout the human body are targets for established therapeutics
and various drugs in development. Their diversity of structure and function reflects the …

Serotonin, 5-hydroxytryptamine (5-HT), is one of the class of monoamine neurontransmitters,
all of which have a chemical template comprised of a basic amino group separated from an …

Fluorescence and bioluminescence resonance energy transfer (FRET and BRET)
techniques allow the sensitive monitoring of distances between two labels at the nanometer …

Serotonin (5‐HT) induces concentration‐dependent metabolic effects in diverse cell types,
including neurons, entherochromaffin cells, adipocytes, pancreatic beta‐cells, fibroblasts …

The broadly distributed monoaminergic neurotransmitter serotonin (5-hydroxytryptamine, 5-
HT) exerts its actions via 14 classes of receptor. With the exception of 5-HT 3 receptors …

The technique of cryogenic-electron microscopy (cryo-EM) has revolutionized the field of
membrane protein structure and function with a focus on the dominantly observed molecular …

The receptor for advanced glycated end products (RAGE) is a multiligand receptor that is
implicated in the pathogenesis of various diseases, including diabetic complications …

Adenosine A2A-dopamine D2 receptor interactions play a very important role in striatal
function. A2A-D2 receptor interactions provide an example of the capabilities of information …

G-protein-coupled receptors (GPCRs) participate in virtually all physiological processes.
They constitute the largest and most structurally conserved family of signaling molecules …

The amyloid precursor protein (APP) is a transmembrane protein that plays major roles in
the regulation of several important cellular functions, especially in the nervous system …