Cancer is one of the leading causes of death and morbidity with a complex pathophysiology.
Traditional cancer therapies include chemotherapy, radiation therapy, targeted therapy, and …

Cancer is the second worldwide cause of death, exceeded only by cardiovascular diseases.
It is characterized by uncontrolled cell proliferation and an absence of cell death that, except …

In the United States, the estimated number of new cancer cases in 2018 will be approx. 1.7
million. Historically, combination chemotherapy has been the primary choice of treatment …

Different mechanisms in cancer cells become resistant to one or more chemotherapeutics is
known as multidrug resistance (MDR) which hinders chemotherapy efficacy. Potential …

The principle mechanism of protection of stem cells is through the expression of ATP‐
binding cassette (ABC) transporters. These transporters serve as the guardians of the stem …

Abstract Poly-ε-caprolactone (PCL) has been the subject of extensive research in the past
few years. It is widely explored in drug delivery, where the development of nanomedicines …

Introduction: Poly (ϵ-caprolactone)(PCL), a biodegradable and biocompatible polymer, is
useful to encapsulate a wide range of drugs making it an interesting material for the …

Resveratrol and curcumin are natural antioxidants found in the human diet that have been
used in the prevention and treatment of different diseases associated with oxidative stress …

Drug delivery to the brain represents a challenge, especially in the therapy of central
nervous system malignancies. Simvastatin (SVT), as with other statins, has shown potential …

Glioblastoma (GBM) is the most lethal form of brain tumor, being characterized by the rapid
growth and invasion of the surrounding tissue. The current standard treatment for …