Peritumoral tissue (PTT): increasing need for naming convention
Various terms are used to describe non-malignant tissue located in the proximity of a tumor,
belonging to the organ from which the tumor originated. Traditionally, these tissues …
belonging to the organ from which the tumor originated. Traditionally, these tissues …
High‐confidence calling of normal epithelial cells allows identification of a novel stem‐like cell state in the colorectal cancer microenvironment
Single‐cell analyses can be confounded by assigning unrelated groups of cells to common
developmental trajectories. For instance, cancer cells and admixed normal epithelial cells …
developmental trajectories. For instance, cancer cells and admixed normal epithelial cells …
uniLIVER: a human liver cell atlas for data-driven cellular state map**
The liver performs several vital functions such as metabolism, toxin removal, and glucose
storage through the coordination of various cell types. With the recent breakthrough of the …
storage through the coordination of various cell types. With the recent breakthrough of the …
[HTML][HTML] Changes in the Expression of Genes Regulating the Response to Hypoxia, Inflammation, Cell Cycle, Apoptosis, and Epithelial Barrier Functioning during …
D Dzhalilova, M Silina, I Tsvetkov, A Kosyreva… - International Journal of …, 2024 - mdpi.com
One of the factors contributing to colorectal cancer (CRC) development is inflammation,
which is mostly hypoxia-associated. This study aimed to characterize the morphological and …
which is mostly hypoxia-associated. This study aimed to characterize the morphological and …
Celecoxib Suppresses NF-κB p65 (RelA) and TNFα Expression Signaling in Glioblastoma
Background: Glioblastoma (GBM) harbors significant genetic heterogeneity, high infiltrative
capacity, and patterns of relapse following many therapies. The expression of nuclear factor …
capacity, and patterns of relapse following many therapies. The expression of nuclear factor …
[HTML][HTML] Investigation of Exome-Wide Tumor Heterogeneity on Colorectal Tissue-Based Single Cells
N Szakállas, A Kalmár, BK Barták… - International …, 2025 - pmc.ncbi.nlm.nih.gov
The progression of colorectal cancer is strongly influenced by environmental and genetic
conditions. One of the key factors is tumor heterogeneity which is extensively studied by …
conditions. One of the key factors is tumor heterogeneity which is extensively studied by …
High expression of BBOX1 in paracancerous tissue is associated with poor prognosis in hepatocellular carcinoma patients
R Fang, Y Zhan, X Dong, S Li, M Yang, Y Zhao… - Scientific Reports, 2024 - nature.com
The molecular profile of paracancerous tissue has been reported to be prognostic for
recurrence in patients with different cancers. This study investigated the clinical significance …
recurrence in patients with different cancers. This study investigated the clinical significance …
Intra Operative Mild Cooling of Large Tumors Reduces Their Invasive and Metastatic Functions While Increasing Their Resistance to Apoptosis
Cancer treatment often involves excisional surgery, but this approach may leave behind
minimal residual disease, leading to tumor regrowth. Proinflammatory cytokines and their …
minimal residual disease, leading to tumor regrowth. Proinflammatory cytokines and their …
TGFβ1, SMAD2, CTNNβ1, and Wnt3a gene mutational status and serum concentrations in individuals with non-small cell lung cancer
HA Omer, K Amin - Cellular and Molecular Biology, 2023 - cellmolbiol.org
Cancer is a disease that can affect almost all biological human tissues and is currently one
of the leading causes of death worldwide (1). GLOBOCAN 2020 indicates lung cancer is the …
of the leading causes of death worldwide (1). GLOBOCAN 2020 indicates lung cancer is the …
TGFβ1, SMAD2, CTNNβ1, and Wnt3a gene mutational status and serum concentrations in individuals with non-small cell lung cancer: Biomarkers in patients with Non …
H Abdalla Omer, K Amin - Cellular and Molecular Biology, 2023 - diva-portal.org
Cancer is a disease that can affect almost all biological human tissues and is currently one
of the leading causes of death worldwide (1). GLOBOCAN 2020 indicates lung cancer is the …
of the leading causes of death worldwide (1). GLOBOCAN 2020 indicates lung cancer is the …